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Immunogen sequence: LTGETINVDR ALKVLTRRLC QDTPNVCLML ETVTVSGCRR LTDRGLYTIA QCCPELRRLE VSGCYNISNE AVFDVVSLC
Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 99%.
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains several tandem leucine-rich repeats.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: F-box and leucine-rich repeat protein 7; F-box protein FBL6/FBL7; F-box protein Fbl7; F-box/LRR-repeat protein 7
Gene Aliases: FBL6; FBL7; FBXL7; KIAA0840
UniProt ID: (Human) Q9UJT9
Entrez Gene ID: (Human) 23194
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