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Suggested positive control: antigen standard for FBXO27 (transient overexpression lysate).
F-box proteins, a critical component of the evolutionary conserved ubiquitin-protein ligase complex SCF (Skp1/Cdc53-Cullin1/F-box), recruit substrates for ubiquitination and consequent degradation through their specific protein-protein interaction domains. Novel human F-box proteins named FBG1, FBG2, FBG3, FBG4 and FBG5 constitute a third subfamily of mammalian F-box proteins. FBG genes are expressed in a limited number of human tissues including kidney, liver, brain and muscle tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: F Box Gama 5; F-box only protein 27; F-box protein FBG5; F-box/G-domain protein 5; rCG54033-like
Gene Aliases: E130008B10Rik; FBG5; FBX27; FBXO27; Gm161; RGD1563982
UniProt ID: (Human) Q8NI29, (Mouse) Q6DIA9
Entrez Gene ID: (Human) 126433, (Mouse) 233040, (Rat) 499114
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