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          • Primary Antibodies ›
          • FBXO4 Antibodies

          Bioss

          FBXO4 Polyclonal Antibody

          View all (12) FBXO4 antibodies

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          Cite FBXO4 Polyclonal Antibody

          Additional Information:
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          Product Details

          BS-9087R

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:2,000
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:100-1:500
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          KLH conjugated synthetic peptide derived from human FBXO4.

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Amount

          100 µg

          Purification

          Protein A

          Storage buffer

          0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol

          Contains

          0.02% ProClin 300

          Storage conditions

          -20°C

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Target Information

          This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternative splicing of this gene generates 2 transcript variants.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: F-box only protein 4; F-box protein Fbx4; unnamed protein product

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          Gene Aliases: 1700096C12Rik; AI851261; AW494535; FBX4; FBXO4

          View more View less

          UniProt ID: (Human) Q9UKT5, (Mouse) Q8CHQ0

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          Entrez Gene ID: (Human) 26272, (Mouse) 106052, (Rat) 310363

          View more View less

          Function(s)
          ubiquitin-protein transferase activity protein binding protein homodimerization activity ubiquitin protein ligase activity protein binding, bridging involved in substrate recognition for ubiquitination
          Process(es)
          protein polyubiquitination telomere maintenance ubiquitin-dependent protein catabolic process protein ubiquitination SCF-dependent proteasomal ubiquitin-dependent protein catabolic process positive regulation of protein ubiquitination cytoplasmic translational initiation regulation of macromolecule biosynthetic process posttranscriptional regulation of gene expression cellular homeostasis regulation of protein stability protein destabilization positive regulation of telomere maintenance via telomerase common myeloid progenitor cell proliferation positive regulation of translation negative regulation of fibroblast proliferation cellular response to ionizing radiation cellular senescence membraneless organelle assembly negative regulation of protein localization to nucleus positive regulation of protein polyubiquitination regulation of DNA damage checkpoint
          It has to be done as per old AB suggested Products section.

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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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