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Proteintech
FBXO5 Polyclonal Antibody
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Product Details
10872-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
FBXO5 Fusion Protein Ag1296 (1-447 aa encoded by BC018905)
Conjugate
Form
Liquid
Concentration
0.42 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MSRRPCSCA LRPPRCSCSA SPSAVTAAGR PRPSDSCKEE SSTLSVKMKC DFNCNHVHSG LKLVKPDDIG RLVSYTPAYL EGSCKDCIKD YERLSCIGSP IVSPRIVELE TESKRLHNKE NQHVQQTLNS TNEIEALETS RLYEDSGYSS FSLQSGLSEH EEGSLLEENF GDSLQSCLLQ IQSPDQYPNK NLLPVLHFEK VVCSTLKKNA KRNPKVDREM LKEIIARGNF RLQNIIGRKM GLECVDILSE LFRRGLRHVL ATILAQLSDM DLINVSKVST TWKKILEDDK GAFQLYSKAI QRVTENNNKF SPHASTREYV MFRTPLASVQ KSAAQTSLKK DAQTKLSNQG DQKGSTYSRH NEFSEVAKTL KKNESLKACI RCNSPAKYDC YLQRATCKRE GCGFDYCTKC LCNYHTTKDC SDGKLLKASC KIGPLPGTKK SKKNLRRL (1-447 aa encoded by BC018905)
Target Information
F-box proteins, critical components of the conserved ubiquitin-protein ligase complex SCF (Skp1/Cdc53-Cullin1/F-box), recruit substrates for ubiquitination and consequent degradation through their specific protein-protein interaction domains. Novel human F-box proteins named FBG1, FBG2, FBG3, FBG4 and FBG5 constitute a subfamily of mammalian F-box proteins. FBG genes are expressed in a limited number of human tissues including kidney, liver, brain and muscle tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Early mitotic inhibitor 1; f-box only protein 31; F-box only protein 5; F-box protein Fbx5; fbxo5
Gene Aliases: 2510044I10Rik; C85305; EMI1; FBX5; Fbxo31; FBXO5
UniProt ID: (Human) Q9UKT4, (Mouse) Q7TSG3
Entrez Gene ID: (Human) 26271, (Mouse) 67141, (Rat) 292263
oocyte maturation
cell cycle
spindle assembly involved in female meiosis I
mitotic nuclear division
regulation of mitotic cell cycle
vesicle organization
regulation of meiotic nuclear division
negative regulation of meiotic nuclear division
microtubule polymerization
spindle assembly
cell division
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
negative regulation of ubiquitin-protein ligase activity involved in meiotic cell cycle
positive regulation of meiosis I
obsolete inhibition of APC-Cdc20 complex activity
G1/S transition of mitotic cell cycle
regulation of transcription involved in G1/S transition of mitotic cell cycle
regulation of mitotic nuclear division
positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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