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Invitrogen
FBXW2 Polyclonal Antibody
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Product Details
PA5-64343
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human FBXW2. Recombinant protein control fragment (Product #RP-103661).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Amount
5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: LYIMDLRTES LISRWPLPEY RKSKRGSSFL AGEASWLNGL DGHNDTGLVF ATSMPDHSIH LVLWKEHG
Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 100%.
Target Information
F-box proteins are an expanding family of eukaryotic proteins characterized by an approximately 40 amino acid motif, the F box. Some F-box proteins have been shown to be critical for the ubiquitin-mediated degradation of cellular regulatory proteins. In fact, F-box proteins are one of the four subunits of ubiquitin protein ligases, called SCFs. SCF ligases bring ubiquitin conjugating enzymes to substrates that are specifically recruited by the different F-box proteins. Mammalian F-box proteins are classified into three groups based on the presence of either WD-40 repeats, leucine-rich repeats, or the presence or absence of other protein-protein interacting domains. This gene encodes the second identified member of the F-box gene family and contains multiple WD-40 repeats.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: contains WD repeats; F-box and WD-40 domain protein 2; F-box and WD-40 domain-containing protein 2; F-box protein Fbw2; F-box/WD repeat-containing protein 2; MGC117371; Protein MD6; unnamed protein product
Gene Aliases: FBW2; FBXW2; FWD2; Md6
UniProt ID: (Human) Q9UKT8
Entrez Gene ID: (Human) 26190
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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