Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
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Recommended positive controls: Raji, K562.^M
^M
Predicted reactivity: Rhesus Monkey (93%), Chimpanzee (97%).^M
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Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CD89; Fc alpha receptor; Fc fragment of IgA, receptor for; IgA Fc receptor; Immunoglobulin alpha Fc receptor
Gene Aliases: CD89; CTB-61M7.2; FcalphaRI; FCAR
UniProt ID: (Human) Q1AJL9
Entrez Gene ID: (Human) 2204
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