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          • Primary Antibodies ›
          • CD32b (FCGR2B) Antibodies

          Invitrogen

          FCGR2B Polyclonal Antibody

          View all (35) CD32b (FCGR2B) antibodies

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          Cite FCGR2B Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (8)
          FCGR2B Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.
          FCGR2B Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 8

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          FCGR2B Antibody (PA5-18362) in ICC/IF

          Immunocytochemistry analysis of paraformaldehyde fixed THP-1 cells immobilized on ShifixTM coverslip, permeabilized with 0.15% Triton. Samples were incubated with FCGR2B polyclonal antibody (Product # PA5-18362) using a dilution of 10 µg/mL for 1 hr followed by Alexa Fluor 488 secondary antibody (2 µg/mL), showing membrane staining. The nuclear stain is DAPI (blue). Negative control: Unimmunized goat IgG (10 µg/mL) followed by Alexa Fluor 488 secondary antibody (2 µg/mL). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
          Published figure supplied by benchsci-logo
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          FCGR2B Antibody in Immunocytochemistry (ICC/IF)
          FCGR2B Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          FCGR2B Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          FCGR2B Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          FCGR2B Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          FCGR2B Antibody in Western Blot (WB)
          FCGR2B Antibody in Western Blot (WB)
          FCGR2B Antibody in Flow Cytometry (Flow)
          FCGR2B Polyclonal Antibody

          Product Details

          PA5-18362

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          0.3-1 µg/mL
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          6-8 µg/mL
          -

          Immunocytochemistry (ICC/IF)

          10 µg/mL
          -

          Flow Cytometry (Flow)

          10 µg/mL
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Goat / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Synthetic peptide sequence (PDALEEPDDQNRI) corresponding to the C-terminus amino acids of FCGR2B (aa 298-310).
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.5 mg/mL

          Amount

          100 µg

          Purification

          Ammonium sulfate precipitation

          Storage buffer

          TBS, pH 7.3, with 0.5% BSA

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C, Avoid Freeze/Thaw Cycles

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_11007517

          Product Specific Information

          This antibody is tested in Peptide ELISA: antibody detection limit dilution 32,000.

          Target Information

          This gene encodes one member of a family of immunoglobulin Fc receptor genes found on the surface of many immune response cells. The protein encoded by this gene is a cell surface receptor found on phagocytic cells such as macrophages and neutrophils, and is involved in the process of phagocytosis and clearing of immune complexes. Alternative splicing results in multiple transcript variants.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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          Cite this product

          Bioinformatics

          Protein Aliases: CD32; CD32 receptor 2; CD32 receptor 2a; CD32 receptor 2b; CD32A; CDw32; Fc fragment of IgG receptor IIb; Fc fragment of IgG, low affinity II, receptor for (CD32); Fc fragment of IgG, low affinity IIb, receptor (CD32); Fc fragment of IgG, low affinity IIb, receptor for (CD32); Fc gamma RIIb; fc-gamma RII-a; Fc-gamma RII-b; Fc-gamma RII-c; fc-gamma-RIIa; Fc-gamma-RIIb; Fc-gamma-RIIc; FcGR; FCGR2A1; FCGR2B; fcRII-a; fcRII-b; FGFR2B; IgG Fc fragment receptor; IgG Fc fragment receptor precursor; IgG Fc receptor beta-Fc-gamma-RII; IgG Fc receptor II-b; IgG Fc receptor II-c; Low affinity immunoglobulin gamma Fc region receptor II-b; Low affinity immunoglobulin gamma Fc region receptor II-c

          View more View less

          Gene Aliases: CD32; CD32B; FCG2; FcgammaRIIb; FCGR2; FCGR2B; FCGR2C; FcGRIIB; FcRII-c; IGFR2

          View more View less

          UniProt ID: (Human) P31994

          View more View less

          Entrez Gene ID: (Human) 2213

          View more View less

          Function(s)
          beta-amyloid binding protein binding IgG receptor activity low-affinity IgG receptor activity IgG binding macromolecular complex binding
          Process(es)
          antibody-dependent cellular cytotoxicity negative regulation of type I hypersensitivity negative regulation of antibody-dependent cellular cytotoxicity negative regulation of cytokine production immune effector process follicular dendritic cell activation mature B cell differentiation involved in immune response follicular B cell differentiation immune complex clearance by monocytes and macrophages negative regulation of dendritic cell antigen processing and presentation regulation of B cell antigen processing and presentation negative regulation of immunoglobulin production regulation of immune system process regulation of adaptive immune response negative regulation of acute inflammatory response to antigenic stimulus positive regulation of humoral immune response negative regulation of humoral immune response mediated by circulating immunoglobulin receptor-mediated endocytosis phagocytosis phagocytosis, engulfment defense response inflammatory response cell surface receptor signaling pathway response to bacterium immunoglobulin mediated immune response antigen processing and presentation of exogenous peptide antigen via MHC class II cerebellum development negative regulation of B cell proliferation negative regulation of interleukin-10 production positive regulation of tumor necrosis factor production Fc-gamma receptor signaling pathway negative regulation of macrophage activation negative regulation of cytotoxic T cell degranulation regulation of innate immune response mast cell activation positive regulation of JNK cascade negative regulation of phagocytosis positive regulation of phagocytosis negative regulation of immune response negative regulation of B cell receptor signaling pathway negative regulation of B cell activation cellular response to molecule of bacterial origin regulation of immune complex clearance by monocytes and macrophages negative regulation of neutrophil activation regulation of dendritic spine maintenance regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway cellular response to beta-amyloid positive regulation of response to endoplasmic reticulum stress negative regulation of dendritic cell differentiation
          It has to be done as per old AB suggested Products section.

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