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Proteintech
FCN1 Polyclonal Antibody
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Product Details
11775-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
FCN1 Fusion Protein Ag2444 (1-326 aa encoded by BC020635)
Conjugate
Form
Liquid
Concentration
0.17 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MELSGATMA RGLAVLLVLF LHIKNLPAQA ADTCPEVKVV GLEGSDKLTI LRGCPGLPGA PGPKGEAGVI GERGERGLPG APGKAGPVGP KGDRGEKGMR GEKGDAGQSQ SCATGPRNCK DLLDRGYFLS GWHTIYLPDC RPLTVLCDMD TDGGGWTVFQ RRMDGSVDFY RDWAAYKQGF GSQLGEFWLG NDNIHALTAQ GSSELRVDLV DFEGNHQFAK YKSFKVADEA EKYKLVLGAF VGGSAGNSLT GHNNNFFSTK DQDNDVSSSN CAEKFQGAWW YADCHASNLN GLYLMGPHES YANGINWSAA KGYKYSYKVS EMKVRPA (1-326 aa encoded by BC020635)
Target Information
M-Ficolin (Ficolin-1) is a non-serum protein that is expressed in leukocytes and lung. M-Ficolin precipitates with mannose-binding lectin (MBL)-associated serine proteases (MASP)-1 and MASP-2, indicating that M-Ficolin forms complexes with MASP-1 and MASP-2, recognizes certain types of bacteria and subsequently activates the lectin pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Collagen/fibrinogen domain-containing protein 1; ficolin (collagen/fibrinogen domain-containing) 1; Ficolin-1; Ficolin-A; Ficolin-alpha; M-ficolin; unnamed protein product
Gene Aliases: FCN1; FCNM
UniProt ID: (Human) O00602
Entrez Gene ID: (Human) 2219
complement activation, lectin pathway
activation of membrane attack complex
immune system process
cell surface pattern recognition receptor signaling pathway
proteolysis
complement activation
G-protein coupled receptor signaling pathway
opsonization
zymogen activation
killing of cells of other organism
positive regulation of interleukin-8 production
protein localization to cell surface
recognition of apoptotic cell
innate immune response
negative regulation of viral entry into host cell
protein maturation
positive regulation of opsonization
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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