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Invitrogen
FCRL2 Polyclonal Antibody
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FIGURE: 1 / 1
FCRL2 Antibody (PA5-109719) in WB
Western blot analysis of FCRL2 in extracts of Raji cells. Samples were incubated with FCRL2 Polyclonal antibody (Product # PA5-109719) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.
Product Details
PA5-109719
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 20-100 of human FCRL2 (Q96LA5)
Conjugate
Form
Liquid
Concentration
3.19 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: LTLVAPSSVF EGDSIVLKCQ GEQNWKIQKM AYHKDNKELS VFKKFSDFLI QSAVLSDSGN YFCSTKGQLF LWDKTSNIVK I
Target Information
The FCRL2 gene encodes the protein Fc receptor-like 2, which is part of the Fc receptor-like family involved in immune system regulation. FCRL2 is primarily expressed on the surface of B lymphocytes, where it contributes to the modulation of B cell activation and immune responses. As a member of the Fc receptor-like family, FCRL2 is thought to play roles in signaling pathways that influence B cell development, differentiation, and antibody production. It may act as a regulatory receptor that balances immune activation and inhibition, thereby contributing to immune homeostasis and prevention of autoimmunity. The expression of FCRL2 can impact conditions such as autoimmune diseases and B cell-related disorders, where dysregulation of B cell signaling is evident. Research into FCRL2 is ongoing to explore its specific ligand interactions and functional mechanisms, aiming to understand its potential as a therapeutic target for modulating immune responses in diseases characterized by B cell dysfunction.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD307b; Fc receptor homolog 2; Fc receptor-like 2; Fc receptor-like protein 2; FcR-like protein 2; FcRH2; IFGP family protein 4; immune receptor translocation-associated protein 4; Immunoglobulin receptor translocation-associated protein 4; immunoglobulin superfamily Fc receptor, gp42; RP11-367J7.6; SH2 domain containing phosphatase anchor protein 1; SH2 domain-containing phosphatase anchor protein 1
Gene Aliases: CD307b; FCRH2; FCRL2; IFGP4; IRTA4; SPAP1; SPAP1A; SPAP1B; SPAP1C; UNQ9236/PRO31998
UniProt ID: (Human) Q96LA5
Entrez Gene ID: (Human) 79368
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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