Immunogen sequence: PILDPVDFLG LQDKIKEVPR PRKRLTELLL RTATEKPGPA EAARQASASR AWGLRFFRSP QQVLPSPDGR RAAGVRLAVT RLEGVDEATR AVPTGDMEDL PCGLVLSSIG YKSRPVDPSV PFDSKLGVIP NVEGRVMDVP GLYCSGWVKR GPTGVIATTM TDSFLTGQML LQDLKAGLLP SGPRPGYAAI QALLSSRGVR PVSFSDWEKL DAEEVARGQG TGKPREKLVD PQEMLRLLGH; Positive Samples: HepG2, NCI-H460, Mouse kidney, Mouse testis, Mouse ovary, Rat lung, Rat kidney; Cellular Location: Mitochondrion matrix
This gene encodes a member of the prefoldin beta subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils.
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Protein Aliases: adrenodoxin reductase; adrenodoxin-NADP(+) reductase; AR; Ferredoxin reductase; Ferredoxin--NADP(+) reductase; NADPH:adrenodoxin oxidoreductase, mitochondrial
Gene Aliases: ADXR; AR; FDXR