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Immunogen sequence: PILDPVDFLG LQDKIKEVPR PRKRLTELLL RTATEKPGPA EAARQASASR AWGLRFFRSP QQVLPSPDGR RAAGVRLAVT RLEGVDEATR AVPTGDMEDL PCGLVLSSIG YKSRPVDPSV PFDSKLGVIP NVEGRVMDVP GLYCSGWVKR GPTGVIATTM TDSFLTGQML LQDLKAGLLP SGPRPGYAAI QALLSSRGVR PVSFSDWEKL DAEEVARGQG TGKPREKLVD PQEMLRLLGH; Positive Samples: HepG2, NCI-H460, Mouse kidney, Mouse testis, Mouse ovary, Rat lung, Rat kidney; Cellular Location: Mitochondrion matrix
This gene encodes a member of the prefoldin beta subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: adrenodoxin reductase; adrenodoxin-NADP(+) reductase; AR; Ferredoxin reductase; Ferredoxin--NADP(+) reductase; NADPH:adrenodoxin oxidoreductase, mitochondrial
Gene Aliases: ADXR; AR; FDXR
UniProt ID: (Human) P22570, (Rat) P56522, (Mouse) Q61578
Entrez Gene ID: (Human) 2232, (Rat) 79122, (Mouse) 14149
Molecular Function:
dehydrogenase
oxidoreductase
reductase
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