Invitrogen

FDXR Polyclonal Antibody

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FDXR Antibody in Immunohistochemistry (IHC) — Immunohistochemistry analysis of FDXR in paraffin-embedded human liver cancer using FDXR Polyclonal Antibody (Product # PA5-96260) at a dilution of 1:100.

FDXR Antibody in Western Blot (WB) — Western Blot analysis of FDXR in extracts of various cell lines using FDXR Polyclonal Antibody (Product # PA5-96260) at a dilution of 1:1000. A HRP Goat Anti-Rabbit IgG (H+L) secondary antibody was used at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST.

Product Details

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:100 - 1:200

Western Blot (WB)

1:500 - 1:2000

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host / Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 252-491 of human FDXR.

Conjugate

Unconjugated

Form

Liquid

Concentration

3.99 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

RRID

AB_2808062

Product Specific Information

Immunogen sequence: PILDPVDFLG LQDKIKEVPR PRKRLTELLL RTATEKPGPA EAARQASASR AWGLRFFRSP QQVLPSPDGR RAAGVRLAVT RLEGVDEATR AVPTGDMEDL PCGLVLSSIG YKSRPVDPSV PFDSKLGVIP NVEGRVMDVP GLYCSGWVKR GPTGVIATTM TDSFLTGQML LQDLKAGLLP SGPRPGYAAI QALLSSRGVR PVSFSDWEKL DAEEVARGQG TGKPREKLVD PQEMLRLLGH; Positive Samples: HepG2, NCI-H460, Mouse kidney, Mouse testis, Mouse ovary, Rat lung, Rat kidney; Cellular Location: Mitochondrion matrix

Target Information

This gene encodes a member of the prefoldin beta subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: adrenodoxin reductase; adrenodoxin-NADP(+) reductase; AR; Ferredoxin reductase; Ferredoxin--NADP(+) reductase; NADPH:adrenodoxin oxidoreductase, mitochondrial

Gene Aliases: ADXR; AR; FDXR

UniProt ID: (Human) P22570, (Rat) P56522, (Mouse) Q61578

Entrez Gene ID: (Human) 2232, (Rat) 79122, (Mouse) 14149

Molecular Function: dehydrogenase oxidoreductase reductase