Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
1:500-1:2,000 | View 4 publications 4 publications |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:100-1:400 | - |
Product Specifications | |
---|---|
Species Reactivity |
Human, Mouse, Rat |
Published species |
Human, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
FECH Fusion Protein Ag5814 (60-423 aa encoded by BC039841) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.18 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20°C |
Immunogen sequence: VQPQKRKPK TGILMLNMGG PETLGDVHDF LLRLFLDRDL MTLPIQNKLA PFIAKRRTPK IQEQYRRIGG GSPIKIWTSK QGEGMVKLLD ELSPNTAPHK YYIGFRYVHP LTEEAIEEME RDGLERAIAF TQYPQYSCST TGSSLNAIYR YYNQVGRKPT MKWSTIDRWP THHLLIQCFA DHILKELDHF PLEKRSEVVI LFSAHSLPMS VVNRGDPYPQ EVSATVQKVM ERLEYCNPYR LVWQSKVGPM PWLGPQTDES IKGLCERGRK NILLVPIAFT SDHIETLYEL DIEYSQVLAK ECGVENIRRA ESLNGNPLFS KALADLVHSH IQSNELCSKQ LTLSCPLCVN PVCRETKSFF TSQQL (60-423 aa encoded by B C039841)
The protein encoded by this gene is localized to the mitochondrion, where it catalyzes the insertion of the ferrous form of iron into protoporphyrin IX in the heme synthesis pathway. Mutations in this gene are associated with erythropoietic protoporphyria. Two transcript variants encoding different isoforms have been found for this gene. A pseudogene of this gene is found on chromosome 3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Ferrochelatase, mitochondrial; Heme synthase; heme synthetase; Protoheme ferro-lyase; protoporphyria
Gene Aliases: AI894116; EPP; FCE; fch; Fcl; FECH
UniProt ID: (Human) P22830, (Mouse) P22315
Entrez Gene ID: (Human) 2235, (Rat) 361338, (Mouse) 14151
Molecular Function:
lyase
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