Recommended positive controls: U87-MG.
Predicted reactivity: Mouse (87%), Rat (89%), Bovine (88%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene is an ortholog of the C. elegans unc-76 gene, which is necessary for normal axonal bundling and elongation within axon bundles. Expression of this gene in C. elegans unc-76 mutants can restore to the mutants partial locomotion and axonal fasciculation, suggesting that it also functions in axonal outgrowth. The N-terminal half of the gene product is highly acidic. Alternatively spliced transcript variants encoding different isoforms of this protein have been described.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: F37; fasciculation and elongation protein zeta 1 (zygin I); Fasciculation and elongation protein zeta-1; zygin 1; Zygin I; Zygin-1
Gene Aliases: FEZ1; UNC-76
UniProt ID: (Human) Q99689
Entrez Gene ID: (Human) 9638