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Rockland
FEZ2 Polyclonal Antibody
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FIGURE: 1 / 3
FEZ2 Antibody (600-401-BE2) in ICC/IF
Immunofluorescence Microscopy of FEZ2 antibody. Tissue: Human brain tissue. Fixation: 0.5% PFA. Antigen retrieval: not required. Primary antibody: FEZ2 antibody at 5 µg/mL for 1 hr at RT. Secondary antibody: Fluorescein rabbit secondary antibody at 1:10,000 for 45 min at RT. Staining: FEZ2 as a red fluorescent signal.
Product Details
600-401-BE2
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Anti-FEZ2 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 15 amino acid synthetic peptide from near the C-terminus of human FEZ2.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.2
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Fasciculation and elongation protein zeta-2 (FEZ2) is a homolog to the mammalian FEZ1, itself an ortholog of the C. elegans UNC-76. In contrast to FEZ1, FEZ2 mRNA is widely expressed in mouse tissues. FEZ2 interacts with protein kinase C (PKC)-zeta substrate and induces neurite extension of PC12 cells when co-expressed with a constitutively active form of PKC-zeta, suggesting FEZ2 may play an important role in the morphological changes of various cells by associating with PKC-zeta in a tissue non-specific manner. FEZ2 can interact with FEZ1 through its c-terminal regions and especially its coiled-coil region. At least two isoforms of FEZ2 are known to exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: fasciculation and elongation protein zeta 2 (zygin II); Fasciculation and elongation protein zeta-2; pre-T/NK cell associated protein (3Cl); synaptotagmin interacting protein zyginII; zygin 2; Zygin II; Zygin-2; Zygin-related protein types I/II
Gene Aliases: 9030616F16; D17Ertd315e; FEZ2; HUM3CL; Zrp
UniProt ID: (Human) Q9UHY8, (Mouse) Q6TYB5, (Rat) P97578
Entrez Gene ID: (Human) 9637, (Mouse) 225020, (Rat) 94269
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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