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Invitrogen
FEZ2 Polyclonal Antibody
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Product Details
PA5-57491
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human FEZ2. Recombinant protein control fragment (Product #RP-102443).
Conjugate
Form
Liquid
Concentration
0.7 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: GSYEERVKRL SVSELNEILE EIETAIKEYS EELVQQLALR DELEFEKEVK NSFISVLIEV QNKQKEHKET AKKKKKLKNG SSQNGKNERS HMPGTYLTTV IPYEKKNGPP SVEDLQILTK ILRAMKEDSE KVPSLLTDYI L
Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 95%.
Target Information
Fasciculation and elongation protein zeta-2 (FEZ2) is a homolog to the mammalian FEZ1, itself an ortholog of the C. elegans UNC-76. In contrast to FEZ1, FEZ2 mRNA is widely expressed in mouse tissues. FEZ2 interacts with protein kinase C (PKC)-zeta substrate and induces neurite extension of PC12 cells when co-expressed with a constitutively active form of PKC-zeta, suggesting FEZ2 may play an important role in the morphological changes of various cells by associating with PKC-zeta in a tissue non-specific manner. FEZ2 can interact with FEZ1 through its c-terminal regions and especially its coiled-coil region. At least two isoforms of FEZ2 are known to exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: fasciculation and elongation protein zeta 2 (zygin II); Fasciculation and elongation protein zeta-2; pre-T/NK cell associated protein (3Cl); zygin 2; Zygin II; Zygin-2
Gene Aliases: FEZ2; HUM3CL
UniProt ID: (Human) Q9UHY8
Entrez Gene ID: (Human) 9637
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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