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Invitrogen
FEZF1 Polyclonal Antibody
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Product Details
PA5-43562
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide directed towards the C-terminal of human FEZF1 (aa 402-451).
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS with 2% sucrose
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Peptide sequence: CPTCGKGFCR NFDLKKHVRK LHDSSLGLAR TPAGEPGTEP PPPLPQQPPM
Sequence homology: Guinea Pig: 79%; Horse: 79%; Human: 100%; Rabbit: 92%; Rat: 100%
Target Information
Transcription repressor. Involved in the axonal projection and proper termination of olfactory sensory neurons (OSN). Plays a role in rostro-caudal patterning of the diencephalon and in prethalamic formation. Expression is required in OSN to cell-autonomously regulate OSN axon projections. Regulates non-cell-autonomously the layer formation of the olfactory bulb development and the interneurons. May be required for correct rostral migration of the interneuron progenitors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Fez family zinc finger protein 1; Zinc finger protein 312B
Gene Aliases: FEZ; FEZF1; HH22; ZNF312B
UniProt ID: (Human) A0PJY2
Entrez Gene ID: (Human) 389549
negative regulation of transcription from RNA polymerase II promoter
neuron migration
transcription, DNA-templated
axon guidance
negative regulation of cell proliferation
olfactory bulb development
forebrain anterior/posterior pattern specification
positive regulation of neuron differentiation
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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