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Invitrogen
FEZF1 Polyclonal Antibody
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FIGURE: 1 / 2
FEZF1 Antibody (PA5-97744) in IHC (P)
Immunohistochemical analysis of FEZF1 in paraffin embedded human brain tissue using a FEZF1 polyclonal antibody (Product # PA5-97744) at a dilution of 1:400. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detect... View More
Product Details
PA5-97744
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human Fez family zinc finger protein 1 protein (1-115AA)
Conjugate
Form
Liquid
Concentration
3.915 mg/mL
Amount
100 µg
Purification
Protein G
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.03% ProClin 300
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
Transcription repressor. Involved in the axonal projection and proper termination of olfactory sensory neurons (OSN). Plays a role in rostro-caudal patterning of the diencephalon and in prethalamic formation. Expression is required in OSN to cell-autonomously regulate OSN axon projections. Regulates non-cell-autonomously the layer formation of the olfactory bulb development and the interneurons. May be required for correct rostral migration of the interneuron progenitors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Fez family zinc finger protein 1; unnamed protein product; Zinc finger protein 312B
Gene Aliases: FEZ; FEZF1; HH22; ZNF312B
UniProt ID: (Human) A0PJY2
Entrez Gene ID: (Human) 389549
transcription regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
zinc ion binding
sequence-specific DNA binding
metal ion binding
negative regulation of transcription from RNA polymerase II promoter
regulation of transcription from RNA polymerase II promoter
nervous system development
axon guidance
negative regulation of cell proliferation
telencephalon development
olfactory bulb development
forebrain anterior/posterior pattern specification
central nervous system neuron differentiation
cell differentiation
neuron differentiation
forebrain development
cell dedifferentiation
positive regulation of neuron differentiation
positive regulation of transcription, DNA-templated
regulation of neurogenesis
interneuron migration
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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