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FFA2, FFA2 Receptor Antibody (7TM0226N-IC) in IHC (P)
Immunohistochemical identification of FFA2 Receptor in pancreas. Sections were dewaxed, microwaved in citric acid, and incubated with anti-FFA2 (FFA2 Receptor) antibody (7TM0226N-IC) at a dilution of 1:100. Sections were then sequentially treated with biotinylated anti-rabbit IgG and avidin-biotin solution. Color was developed by incubation in 3-amino-9-ethylcarbazole (AEC) , and sections were counterstaine... View More
Product Details
7TM0226N-IC
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide presents the carboxyl - terminal tail of human FFA2.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
Dulbecco's PBS, pH 7.4
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
G protein-coupled receptors (GPCRs, or GPRs) contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. GPCR GPR43 is a member of this family (subfamily carboxylic acid). It expression has been reported primarily in immune cells including monocytes and neutrophils. An EST has been isolated from a human pancreatic library.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: fatty acid receptor 2; free fatty acid activated receptor 2; Free fatty acid receptor 2; G protein-coupled receptor 43; G-protein coupled receptor 43; Leukocyte-specific STAT-induced GPCR
Gene Aliases: FFA2; FFA2R; FFAR2; GPCR43; GPR43; Lssig
UniProt ID: (Human) O15552, (Rat) Q76EI6, (Mouse) Q8VCK6
Entrez Gene ID: (Human) 2867, (Rat) 292794, (Mouse) 233079
leukocyte chemotaxis involved in inflammatory response
mucosal immune response
regulation of acute inflammatory response
positive regulation of cytokine production involved in immune response
cell surface pattern recognition receptor signaling pathway
positive regulation of acute inflammatory response to non-antigenic stimulus
G-protein coupled receptor signaling pathway
lipid storage
positive regulation of chemokine production
glucose homeostasis
fat cell differentiation
cellular response to fatty acid
regulation of peptide hormone secretion
positive regulation of interleukin-8 secretion
biological_process
immune system process
inflammatory response
signal transduction
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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