Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: RAHTSIPLLG YQVTVGPQGD PRVFQLQQSG QLYTFKAETE ELKGRWVKAM ERAASGWSPS WPNDGDLS
Highest antigen sequence identity to the following orthologs: Mouse - 74%, Rat - 76%.
Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Activates JNK1 via CDC42 but not RAC1. Binds to phosphatidylinositol 4,5- bisphosphate, phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 5-monophosphate, phosphatidylinositol 4- monophosphate and phosphatidylinositol 3-monophosphate.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: FGD1 family, member 2; FLJ00276 protein; FYVE, RhoGEF and PH domain-containing protein 2; Zinc finger FYVE domain-containing protein 4
Gene Aliases: FGD2; ZFYVE4
UniProt ID: (Human) Q7Z6J4
Entrez Gene ID: (Human) 221472
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