Immunogen sequence: GEITTFTALT EKFNLPPGNY KKPKLLYCSN GGHFLRILPD GTVDGTRDRS DQHTDTK
Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 88%.
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis. Multiple alternatively spliced variants encoding different isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Acidic fibroblast growth factor; AFGF; Beta-endothelial cell growth factor; ECGF; ECGF-beta; ECGFA; ECGFB; Endothelial cell growth factor; endothelial cell growth factor, alpha; endothelial cell growth factor, beta; FGF-1; FGF-alpha; FGF1; FGFA; Fibroblast growth factor 1; fibroblast growth factor 1 (acidic); HBGF-1; HBGF1; Heparin-binding growth factor 1; Heparin-binding growth factor 1 [Precursor]
Gene Aliases: AFGF; ECGF; ECGF-beta; ECGFA; ECGFB; FGF-1; FGF-alpha; FGF1; FGFA; GLIO703; HBGF-1; HBGF1
UniProt ID: (Human) P05230
Entrez Gene ID: (Human) 2246