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Invitrogen
FGF1 Monoclonal Antibody (C2)
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Product Details
MA566130
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Rat
Host/Isotype
Mouse
Class
Monoclonal
Type
Antibody
Clone
C2
Immunogen
Recombinant Fibroblast Growth Factor 1, Acidic (FGF1) (Phe16-Asp155)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A/G
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
FGF1 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Acidic fibroblast growth factor; aFGF; FGF; FGF-1; Fibroblast growth factor; Fibroblast growth factor 1; Fibroblast growth factor 1 (heparin binding); H-FGF-a; HBGF-1; Heparin-binding growth factor 1; M-FGF-a
Gene Aliases: FGF-1; Fgf1; Fgfa; HBGF-1; HBGF1
UniProt ID: (Rat) P61149
Entrez Gene ID: (Rat) 25317
angiogenesis
organ induction
positive regulation of protein phosphorylation
cell proliferation
positive regulation of cell proliferation
fibroblast growth factor receptor signaling pathway
lung development
positive regulation of cell migration
cellular response to heat
positive regulation of MAP kinase activity
positive regulation of cholesterol biosynthetic process
positive regulation of angiogenesis
positive regulation of transcription from RNA polymerase II promoter
positive regulation of epithelial cell proliferation
positive regulation of cell division
branch elongation involved in ureteric bud branching
mesonephric epithelium development
positive regulation of intracellular signal transduction
regulation of endothelial cell chemotaxis to fibroblast growth factor
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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