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          • Primary Antibodies ›
          • FGF10 Antibodies

          Invitrogen

          FGF10 Polyclonal Antibody

          View all (12) FGF10 antibodies

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          Cite FGF10 Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (1)
          FGF10 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.
          FGF10 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          FGF10 Antibody (720149) in WB

          Western blot analysis was performed on Whole cell extracts (30 µg lysate) of HeLa (Lane 1), HeLa (Condition Media) (Lane 2), HEK-293 (Lane 3), HEK-293 (Condition Media) (Lane 4), A549 (Lane 5), A549 (Condition Media) (Lane 6), Huvec (Lane 7) and Huvec (Condition Media) (Lane 8). The blots were probed with Anti-FGF10 Rabbit Polyclonal Antibody (Product # 720149, 1-2 µg/mL) and detected by chemiluminescence using Goat anti-Rabbit IgG (Heavy Chain) Superclonal Secondary Antibody, HRP conjugate (Product # A27036, 0.4 µg/mL, 1:2500 dilution). A... View More {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          FGF10 Antibody in Western Blot (WB)
          FGF10 Polyclonal Antibody

          Product Details

          720149

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1-2 µg/mL
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Protein corresponding to Human FGF10 (aa 64-208)
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.5 mg/mL

          Purification

          Affinity chromatography

          Storage buffer

          PBS, pH 7.4, with 0.1% BSA, 30% glycerol

          Contains

          0.09% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2633197

          Product Specific Information

          These Polyclonal antibodies are of rabbit origin developed by immunizing animals with proteins or peptides. The polyclonal antibody is purified by affinity purification from the rabbit sera generated after immunizing the rabbits with a specific type of protein or peptide. The purified antibody is tested for its functionality in various relevant research applications. The antibody is developed for Research Use Only and is non-hazardous or non-infectious in nature.

          This antibody is predicted to react with Monkey, Pig, Cat and Horse

          Target Information

          FGF10 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts, which is similar to the biological activity of FGF7. Studies of the mouse homolog of suggested that this gene is required for embryonic epidermal morphogenesis including brain development, lung morphogenesis, and initiation of lim bud formation. This protein is also implicated to be a primary factor in the process of wound healing.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: FGF; FGF-10; FGF10; Fibroblast growth factor; Fibroblast growth factor 10; fibroblast growth factor 10; FGF10; Keratinocyte growth factor 2; keratinocyte growth factor-2; KGF2; produced by fibroblasts of urinary bladder lamina propria

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          Gene Aliases: FGF10; LADD3

          View more View less

          UniProt ID: (Human) O15520

          View more View less

          Entrez Gene ID: (Human) 2255

          View more View less

          Function(s)
          fibroblast growth factor receptor binding type 2 fibroblast growth factor receptor binding protein binding growth factor activity heparin binding chemoattractant activity
          Process(es)
          establishment of mitotic spindle orientation mitotic cell cycle angiogenesis metanephros development organ induction mesonephros development endothelial cell proliferation positive regulation of endothelial cell proliferation blood vessel remodeling metanephros morphogenesis chemotaxis cell-cell signaling determination of left/right symmetry salivary gland development salivary gland morphogenesis cell proliferation positive regulation of cell proliferation fibroblast growth factor receptor signaling pathway epidermis development regulation of smoothened signaling pathway embryonic pattern specification organ morphogenesis regulation of gene expression positive regulation of epithelial cell migration positive regulation of keratinocyte proliferation Wnt signaling pathway pituitary gland development neurogenesis actin cytoskeleton organization cell differentiation positive regulation of Wnt signaling pathway lung development regulation of cell migration embryonic genitalia morphogenesis epithelial cell differentiation negative regulation of epithelial cell differentiation thyroid gland development otic vesicle formation positive regulation of vascular endothelial growth factor receptor signaling pathway pancreas development hair follicle morphogenesis embryonic camera-type eye development response to estradiol response to lipopolysaccharide positive regulation of ATPase activity lacrimal gland development regulation of activin receptor signaling pathway protein localization to cell surface somatic stem cell population maintenance limb morphogenesis organ growth wound healing tissue regeneration inner ear morphogenesis odontogenesis of dentin-containing tooth muscle cell fate commitment positive regulation of MAPK cascade keratinocyte proliferation positive regulation of DNA repair positive regulation of Notch signaling pathway positive regulation of transcription, DNA-templated positive regulation of mitotic cell cycle positive regulation of transcription from RNA polymerase II promoter positive regulation of Ras protein signal transduction regulation of saliva secretion vascular endothelial growth factor receptor signaling pathway fibroblast proliferation positive regulation of fibroblast proliferation lung alveolus development blood vessel morphogenesis spleen development thymus development embryonic digestive tract morphogenesis digestive tract development embryonic digestive tract development organ formation epidermis morphogenesis semicircular canal morphogenesis branching morphogenesis of an epithelial tube female genitalia morphogenesis male genitalia morphogenesis positive regulation of lymphocyte proliferation epithelial cell proliferation urothelial cell proliferation positive regulation of urothelial cell proliferation positive regulation of epithelial cell proliferation positive regulation of peptidyl-tyrosine phosphorylation white fat cell differentiation positive chemotaxis induction of positive chemotaxis smooth muscle cell differentiation positive regulation of keratinocyte migration radial glial cell differentiation positive regulation of epithelial cell proliferation involved in wound healing limb development limb bud formation lung morphogenesis lung epithelium development lung saccule development bronchiole morphogenesis epithelial tube branching involved in lung morphogenesis branching involved in salivary gland morphogenesis bud outgrowth involved in lung branching bud elongation involved in lung branching mesenchymal-epithelial cell signaling involved in lung development Type II pneumocyte differentiation prostatic bud formation respiratory system development mammary gland specification fibroblast growth factor receptor signaling pathway involved in mammary gland specification mammary gland bud formation submandibular salivary gland formation epithelial cell proliferation involved in salivary gland morphogenesis regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling branch elongation involved in salivary gland morphogenesis semicircular canal fusion mesenchymal cell differentiation involved in lung development secretion by lung epithelial cell involved in lung growth lung proximal/distal axis specification tear secretion white fat cell proliferation positive regulation of white fat cell proliferation ERK1 and ERK2 cascade positive regulation of ERK1 and ERK2 cascade Harderian gland development positive regulation of hair follicle cell proliferation stem cell proliferation positive regulation of canonical Wnt signaling pathway extrinsic apoptotic signaling pathway in absence of ligand positive regulation of G1/S transition of mitotic cell cycle fibroblast growth factor receptor apoptotic signaling pathway negative regulation of stem cell proliferation positive regulation of stem cell proliferation negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
          It has to be done as per old AB suggested Products section.

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