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Invitrogen
FGF12 Polyclonal Antibody
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Product Details
PA5-148579
Product Specifications
Species Reactivity
Human
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
E. coli-derived recombinant human FGF-12, Glu67-Thr243
Conjugate
Form
Lyophilized
Concentration
0.2 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS with trehalose
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. This growth factor lacks the N-terminal signal sequence present in most of the FGF family members, but it contains clusters of basic residues that have been demonstrated to act as a nuclear localization signal. When transfected into mammalian cells, this protein accumulated in the nucleus, but was not secreted. The specific function of this gene has not yet been determined. Two alternatively spliced transcript variants encoding distinct isoforms have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FGF; FGF-12; FHF-1; Fibroblast growth factor; Fibroblast growth factor 12; fibroblast growth factor 12B; fibroblast growth factor FGF-12b; Fibroblast growth factor homologous factor 1; Myocyte-activating factor; unnamed protein product
Gene Aliases: DEE47; EIEE47; FGF12; FGF12B; FHF1
UniProt ID: (Human) P61328
Entrez Gene ID: (Human) 2257
signal transduction
JNK cascade
cell-cell signaling
chemical synaptic transmission
nervous system development
heart development
adult locomotory behavior
fibroblast growth factor receptor signaling pathway
positive regulation of sodium ion transport
neurogenesis
neuromuscular process
cardiac muscle cell action potential involved in contraction
regulation of neuronal action potential
regulation of sodium ion transmembrane transport
regulation of voltage-gated sodium channel activity
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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