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Product Details
PA5-142984
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Peptide with sequence KGKTSCDKNKLNVFS (aa 33-47).
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Ammonium sulfate precipitation
Storage buffer
TBS, pH 7.3, with 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2933624
Product Specific Information
Additional Information: This antibody is expected to recognize isoform 1 (NP_004105.1) only.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:32,000.
Target Information
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. This gene is located in a region on chromosome X, which is associated with Borjeson-Forssman-Lehmann syndrome (BFLS), making it a possible candidate gene for familial cases of the BFLS, and for other syndromal and nonspecific forms of X-linked mental retardation mapping to this region. Alternative splicing of this gene at the 5' end results in several transcript variants encoding different isoforms with different N-termini.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: AFGF; ECGF; ECGFA; ECGFB; FGF; FGF 1; FGF alpha; FGF-13; FGF13A; FGFA; FHF-2; Fibroblast growth factor; Fibroblast growth factor 13; Fibroblast growth factor homologous factor 2; GLIO703; HBGF 1; HBGF1
Gene Aliases: Fgf13; Fhf2
UniProt ID: (Mouse) P70377
Entrez Gene ID: (Mouse) 14168
MAPK cascade
neuron migration
apoptotic process
negative regulation of microtubule depolymerization
nervous system development
learning
memory
cell proliferation
hippocampus development
cerebral cortex cell migration
establishment of neuroblast polarity
positive regulation of protein kinase activity
microtubule polymerization
negative regulation of collateral sprouting
protein localization to plasma membrane
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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