FIGURE: 1 / 2
Positive Control: U2OS, human FGF18-transfected 293T
Predicted Reactivity: Mouse (100%), Rat (100%), Chicken (98%), Bovine (100%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
FGF18 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. It has been shown in vitro that this protein is able to induce neurite outgrowth in PC12 cells. Studies of the similar proteins in mouse and chick suggested that this protein is a pleiotropic growth factor that stimulates proliferation in a number of tissues, most notably the liver and small intestine. Knockout studies of the similar gene in mice implied the role of this protein in regulating proliferation and differentiation of midline cerebellar structures.
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For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: FGF; FGF-18; Fibroblast growth factor; Fibroblast growth factor 18; zFGF5
Gene Aliases: FGF-18; FGF18; UNQ420/PRO856; ZFGF5
UniProt ID: (Human) O76093
Entrez Gene ID: (Human) 8817