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FGF20 Polyclonal Antibody
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FIGURE: 1 / 1
FGF20 Antibody (BS-5772R) in IHC (P)
Paraformaldehyde-fixed, paraffin embedded Rat brain; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with FGF20 Polyclonal Antibody, Unconjugated (bs-5772R) at 1:400 overnight at 4°C, DAB staining.
Product Details
BS-5772R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human FGF20, amino acids 25-211.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
FGF-20 is a secreted, heparin-binding growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-20 signals through FGFR 2c and 3c, and is expressed during limb and brain development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FGF; FGF-20; Fibroblast growth factor; Fibroblast growth factor 20
Gene Aliases: FGF-20; FGF20; RHDA2
UniProt ID: (Human) Q9NP95, (Rat) Q9EST9, (Mouse) Q9ESL9
Entrez Gene ID: (Human) 26281, (Rat) 66017, (Mouse) 80857
signal transduction
cell-cell signaling
positive regulation of cell proliferation
fibroblast growth factor receptor signaling pathway
regulation of dopamine secretion
neurogenesis
cell differentiation
regulation of cell migration
auditory receptor cell differentiation
positive regulation of MAPK cascade
negative regulation of neuron apoptotic process
regulation of neuron differentiation
regulation of cardiac muscle cell proliferation
positive regulation of ERK1 and ERK2 cascade
positive regulation of dopaminergic neuron differentiation
inner ear receptor cell differentiation
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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