|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide (120 GMNDKGELYGSEKLTSEC 137) of FGF20 protein.|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS with 0.05% BSA|
|Contains||0.05% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||5 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Fibroblast growth factor 20 belongs to the heparin-binding growth factors family. FGF20 is expressed in normal brain, particularly the cerebellum and in some cancer cell lines. FGF20 has been found to be a critical element in oncogenesis induced by the Wnt signaling pathway. Recombinant FGF20 protein induces DNA synthesis in a variety of cell types and is recognized by multiple FGF receptors. Several reports show FGF20 is responsible for Parkinson and quote;s disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.