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Product Details
PA5-112421
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human Fibroblast growth factor 6 protein (38-208AA)
Conjugate
Unconjugated
Form
Liquid
Concentration
0.78 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C or -80°C if preferred
RRID
AB_2867156
Target Information
FGF-6 is a secreted, heparin-binding growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-6 is expressed in leukemia cell lines with platelet megakaryocytic differentiation potential. It signals through FGFR 1c, 2c, and 4.4
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FGF; FGF-6; Fibroblast growth factor; Fibroblast growth factor 6; HBGF-6; Heparin secretory-transforming protein 2; Heparin-binding growth factor 6; HST-2; HSTF-2
Gene Aliases: FGF6; HBGF-6; HST2; HSTF2
UniProt ID: (Human) P10767
Entrez Gene ID: (Human) 2251
Molecular Function:
growth factor
intercellular signal molecule
MAPK cascade
cartilage condensation
angiogenesis
signal transduction
cell-cell signaling
cell proliferation
positive regulation of cell proliferation
fibroblast growth factor receptor signaling pathway
regulation of phosphatidylinositol 3-kinase signaling
peptidyl-tyrosine phosphorylation
phosphatidylinositol-3-phosphate biosynthetic process
positive regulation of GTPase activity
myoblast differentiation
phosphatidylinositol phosphorylation
phosphatidylinositol-mediated signaling
positive regulation of cell division
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