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Invitrogen

FGF9 Polyclonal Antibody

1 Published Figure
1 Reference
View all (12) FGF9 antibodies

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FGF9 Polyclonal Antibody

Product Details

PA5-103855

Applications
Tested Dilution
Publications

Western Blot (WB)

1:1,000-1:3,000
View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Rabbit

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human FGF9(Accession P31371), corresponding to amino acid residues M1-A42.
3D Epitope / Immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Amount

100 µg

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2853187

Product Specific Information

Antibody detects endogenous levels of total FGF9.

Target Information

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein was isolated as a secreted factor that exhibits a growth-stimulating effect on cultured glial cells. In nervous system, this protein is produced mainly by neurons and may be important for glial cell development. Expression of the mouse homolog of this gene was found to be dependent on Sonic hedgehog (Shh) signaling. Mice lacking the homolog gene displayed a male-to-female sex reversal phenotype, which suggested a role in testicular embryogenesis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: elbow knee synostosis; FGF; FGF-9; Fibroblast growth factor; Fibroblast growth factor 9; fibroblast growth factor 9 (glia-activating factor); GAF; glia activating factor; Glia-activating factor; HBGF-9; Heparin-binding growth factor 9; M-FGF-9; unnamed protein product

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Gene Aliases: Eks; FGF-9; FGF9; GAF; HBFG-9; HBGF-9; SYNS3

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UniProt ID: (Human) P31371, (Rat) P36364, (Mouse) P54130

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Entrez Gene ID: (Human) 2254, (Rat) 25444, (Mouse) 14180

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Function(s)
fibroblast growth factor receptor binding growth factor activity heparin binding receptor binding growth factor intercellular signal molecule
Process(es)
negative regulation of transcription from RNA polymerase II promoter angiogenesis osteoblast differentiation eye development positive regulation of mesenchymal cell proliferation chondrocyte differentiation protein import into nucleus signal transduction smoothened signaling pathway cell-cell signaling cell proliferation positive regulation of cell proliferation fibroblast growth factor receptor signaling pathway male gonad development mesenchymal cell proliferation positive regulation of gene expression Wnt signaling pathway substantia nigra development neurogenesis cell differentiation negative regulation of Wnt signaling pathway male sex determination lung development embryonic limb morphogenesis regulation of cell migration positive regulation of vascular endothelial growth factor receptor signaling pathway activin receptor signaling pathway positive regulation of activin receptor signaling pathway inner ear morphogenesis positive regulation of MAPK cascade positive regulation of smoothened signaling pathway vascular endothelial growth factor receptor signaling pathway regulation of timing of cell differentiation embryonic digestive tract development embryonic skeletal system development epithelial cell proliferation positive regulation of epithelial cell proliferation positive regulation of cell division Sertoli cell proliferation cardiac muscle cell proliferation positive regulation of cardiac muscle cell proliferation canonical Wnt signaling pathway lung-associated mesenchyme development stem cell proliferation positive regulation of canonical Wnt signaling pathway positive regulation of vascular smooth muscle cell proliferation positive regulation of vascular associated smooth muscle cell migration negative regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching positive regulation of stem cell proliferation cardiac left ventricle morphogenesis cardiac ventricle development multicellular organism development positive regulation of transcription, DNA-templated vasculogenesis involved in coronary vascular morphogenesis
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