Search
Abnova
FGL2 Polyclonal Antibody, MaxPab™
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
FIGURE: 1 / 3
FGL2 Antibody (H00010875-D01P) in WB
Western Blot analysis of FGL2 expression in transfected 293T cell line (H00010875-T02) by FGL2 MaxPab polyclonal antibody.
Lane 1: FGL2 transfected lysate(50.20 KDa).
Lane 2: Non-transfected lysate.
Lane 1: FGL2 transfected lysate(50.20 KDa).
Lane 2: Non-transfected lysate.
Product Details
H00010875-D01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
FGL2 (NP_006673.1, 1 a.a. approximately 439 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
See Label
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: MKLANWYWLS SAVLATYGFL VVANNETEEI KDERAKDVCP VRLESRGKCE EAGECPYQVS LPPLTIQLPK QFSRIEEVFK EVQNLKEIVN SLKKSCQDCK LQADDNGDPG RNGLLLPSTG APGEVGDNRV RELESEVNKL SSELKNAKEE INVLHGRLEK LNLVNMNNIE NYVDSKVANL TFVVNSLDGK CSKCPSQEQI QSRPVQHLIY KDCSDYYAIG KRSSETYRVT PDPKNSSFEV YCDMETMGGG WTVLQARLDG STNFTRTWQD YKAGFGNLRR EFWLGNDKIH LLTKSKEMIL RIDLEDFNGV ELYALYDQFY VANEFLKYRL HVGNYNGTAG DALRFNKHYN HDLKFFTTPD KDNDRYPSGN CGLYYSSGWW FDACLSANLN GKYYHQKYRG VRNGIFWGTW PGVSEAHPGG YKSSFKEAKM MIRPKHFKP
Target Information
Fibrinogen-like protein 2 (Fgl2), also known as fibroleukin, is secreted by T cells and is involved in diseases in which thrombosis plays a pivotal role, such as virus-induced fulminant hepatitis, fetal loss syndrome and xenograft rejection. Constitutively expressed in cytotoxic T cells, Fgl2 exerts immunosuppressive effects on both T cell proliferation and dendritic cell maturation. Fgl2 is a serine protease and directly cleaves prothrombin to thrombin. Fgl2 functions in the pathogenesis of diseases including viral-induced hepatitis and Th1 cytokine-induced fetal loss syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: Fibrinogen-like protein 2; Fibroleukin; pT49; unnamed protein product
Gene Aliases: FGL2; pT49; T49
UniProt ID: (Human) Q14314
Entrez Gene ID: (Human) 10875
T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell
negative regulation of dendritic cell antigen processing and presentation
negative regulation of macrophage antigen processing and presentation
negative regulation of memory T cell differentiation
negative regulation of defense response to virus
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support