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Search Thermo Fisher Scientific
Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
1:500-1:2400 | View 14 publications 14 publications |
Immunohistochemistry (IHC) |
- | View 4 publications 4 publications |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:20-1:200 | - |
Immunoprecipitation (IP) |
0.5-4.0 µg | View 2 publications 2 publications |
ChIP assay (ChIP) |
Assay-dependent | View 1 publication 1 publication |
Product Specifications | |
---|---|
Species Reactivity |
Human, Mouse, Rat, Zebrafish |
Published species |
Human, Mouse, Zebrafish |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
FHL1 Fusion Protein Ag1448 (1-280 aa encoded by BC010998) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.13 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20°C |
This is a rabbit polyclonal antibody raised against full length of human FHL1.
Immunogen sequence: MAEKFDCHY CRDPLQGKKY VQKDGHHCCL KCFDKFCANT CVECRKPIGA DSKEVHYKNR FWHDTCFRCA KCLHPLANET FVAKDNKILC NKCTTREDSP KCKGCFKAIV AGDQNVEYKG TVWHKDCFTC SNCKQVIGTG SFFPKGEDFY CVTCHETKFA KHCVKCNKAI TSGGITYQDQ PWHADCFVCV TCSKKLAGQR FTAVEDQYYC VDCYKNFVAK KCAGCKNPIT GFGKGSSVVA YEGQSWHDYC FHCKKCSVNL ANKRFVFHQE QVYCPDCAKK L (1-280 aa encoded by BC010998)
This gene encodes a member of the four-and-a-half-LIM-only protein family. Family members contain two highly conserved, tandemly arranged, zinc finger domains with four highly conserved cysteines binding a zinc atom in each zinc finger. Expression of these family members occurs in a cell- and tissue-specific mode and these proteins are involved in many cellular processes. Mutations in this gene have been found in patients with Emery-Dreifuss muscular dystrophy. Multiple alternately spliced transcript variants which encode different protein isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: bA535K18.1; FHL; FHL-1; four and a half LIM domains a; Four and a half LIM domains protein 1; four-and-a-half Lin11, Isl-1 and Mec-3 domains 1; KYO-T; KyoT; LIM protein SLIMMER; MGC111107; RAM14-1; RBP-associated molecule 14-1; RP11-535K18.1; Skeletal muscle LIM-protein 1; SLIM
Gene Aliases: cb1039; fhl; FHL-1; FHL1; FHL1A; FHL1B; fhla; FLH1A; KYOT; RAM14-1; RBMX1A; RBMX1B; SLIM; SLIM-1; SLIM1; SLIMMER; XMPMA; zgc:92025
UniProt ID: (Human) Q13642, (Rat) Q9WUH4, (Mouse) P97447
Entrez Gene ID: (Human) 2273, (Rat) 25177, (Mouse) 14199, (Zebrafish) 399646, (Zebrafish) 387528
Molecular Function:
transcription cofactor
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