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Proteintech
FHL1 Polyclonal Antibody
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Product Details
10991-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat,
Zebrafish
Published species
Human,
Mouse,
Zebrafish
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
FHL1 Fusion Protein Ag1448 (1-280 aa encoded by BC010998)
Conjugate
Form
Liquid
Concentration
0.13 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
This is a rabbit polyclonal antibody raised against full length of human FHL1.
Immunogen sequence: MAEKFDCHY CRDPLQGKKY VQKDGHHCCL KCFDKFCANT CVECRKPIGA DSKEVHYKNR FWHDTCFRCA KCLHPLANET FVAKDNKILC NKCTTREDSP KCKGCFKAIV AGDQNVEYKG TVWHKDCFTC SNCKQVIGTG SFFPKGEDFY CVTCHETKFA KHCVKCNKAI TSGGITYQDQ PWHADCFVCV TCSKKLAGQR FTAVEDQYYC VDCYKNFVAK KCAGCKNPIT GFGKGSSVVA YEGQSWHDYC FHCKKCSVNL ANKRFVFHQE QVYCPDCAKK L (1-280 aa encoded by BC010998)
Target Information
This gene encodes a member of the four-and-a-half-LIM-only protein family. Family members contain two highly conserved, tandemly arranged, zinc finger domains with four highly conserved cysteines binding a zinc atom in each zinc finger. Expression of these family members occurs in a cell- and tissue-specific mode and these proteins are involved in many cellular processes. Mutations in this gene have been found in patients with Emery-Dreifuss muscular dystrophy. Multiple alternately spliced transcript variants which encode different protein isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: bA535K18.1; FHL; FHL-1; four and a half LIM domains a; Four and a half LIM domains protein 1; four-and-a-half Lin11, Isl-1 and Mec-3 domains 1; KYO-T; KyoT; LIM protein SLIMMER; MGC111107; RAM14-1; RBP-associated molecule 14-1; RP11-535K18.1; Skeletal muscle LIM-protein 1; SLIM
Gene Aliases: cb1039; fhl; FHL-1; FHL1; FHL1A; FHL1B; fhla; FLH1A; KYOT; RAM14-1; RBMX1A; RBMX1B; SLIM; SLIM-1; SLIM1; SLIMMER; XMPMA; zgc:92025
UniProt ID: (Human) Q13642, (Rat) Q9WUH4, (Mouse) P97447
Entrez Gene ID: (Human) 2273, (Rat) 25177, (Mouse) 14199, (Zebrafish) 399646, (Zebrafish) 387528
regulation of membrane depolarization
muscle organ development
organ morphogenesis
negative regulation of G2/M transition of mitotic cell cycle
cell differentiation
negative regulation of cell growth
positive regulation of potassium ion transport
regulation of potassium ion transmembrane transporter activity
negative regulation of G1/S transition of mitotic cell cycle
multicellular organism development
cardiac chamber morphogenesis
cardiac ventricle morphogenesis
cardiac atrium morphogenesis
skeletal muscle tissue development
locomotory behavior
cardiac muscle tissue development
liver development
endocrine pancreas development
calcium ion homeostasis
pancreas regeneration
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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