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Invitrogen
FHOD3 Polyclonal Antibody
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Product Details
PA5-54524
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human FHOD3. Recombinant protein control fragment (Product #RP-88593).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Amount
5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: GVDTELLVYA MTLVNKTLSG LPDQDTFYDV VDCLEELGIA AVSQRHLNKK GTDLDLVEQL NIYEVALRHE DGDETTEPPP SGCRDRRRAS VCSSGGGEHR GLDRRRSRRH SVQSIKSTLS APTSPCSQSA PSFKPNQV
Highest antigen sequence identity to the following orthologs: Mouse - 87%, Rat - 87%.
Target Information
FHOD3 is a novel member of the formin homology family playing an important role in regulation of the actin cytoskeleton. It contains a DAD (diaphanous auto regulatory) domain, an FH1 (formin homology 1) domain, an FH2 (formin homology 2) domain and a GBD/FH3 (Rho GTPase-binding/formin homology 3) domain. FHOD3 is a cytoplasmic protein where the main part of the protein localizes to actin fibers and the remaining part displays filamentous staining. A 1422 amino acid containing formin-related actin-organizing protein, FHOD3 may cause stress fiber formation together with cell elongation and may associate with nestin/NES-based interfilament (IF). Expression of FHOD3 is seen mainly in heart, kidney, and brain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: actin assembly factor; FH1/FH2 domain-containing protein 3; Formactin-2; Formin homolog overexpressed in spleen 2; hFHOS2; unnamed protein product
Gene Aliases: CMH28; FHOD3; FHOS2; Formactin2; KIAA1695
UniProt ID: (Human) Q2V2M9
Entrez Gene ID: (Human) 80206
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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