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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • FIP1L1 Antibodies

          Bethyl Laboratories

          FIP1 Polyclonal Antibody

          View all (13) FIP1L1 antibodies

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          Cite FIP1 Polyclonal Antibody

          • Antibody Testing Data (2)
          FIP1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          FIP1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          FIGURE: 1 / 2

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          FIP1 Antibody (A301-461A) in IHC (P)

          Detection of human FIP1 by immunohistochemistry. Sample: FFPE section of human pancreatic islet cell tumor. Antibody: Affinity purified rabbit anti-FIP1 (Product # A301-461A) used at a dilution of 1:1,000 (1 µg/mL). Detection: DAB. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          FIP1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          FIP1 Antibody in Western Blot (WB)
          FIP1 Polyclonal Antibody

          Product Details

          A301-461A

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:2,000-1:10,000
          -

          Immunohistochemistry (IHC)

          1:500-1:2,000
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:500-1:2,000
          -

          Immunoprecipitation (IP)

          2-5 µg/mg lysate
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Region between residue 1 and 50 of human factor interacting with PAP.
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          tris citrate/phosphate, pH 7-8

          Contains

          0.09% sodium azide

          Storage conditions

          4°C

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Product Specific Information

          The recommended shelf life for this product is 1 year from date of receipt.

          Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

          Based on 100% sequence identity, this antibody is predicted to react with Orangutan

          Target Information

          FIP1L1 is a component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. FIP1L1 contributes to poly(A) site recognition and stimulates poly(A) addition. It binds to U-rich RNA sequence elements surrounding the poly(A) site. FIP1L1 may act to tether poly(A) polymerase to the CPSF complex.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: DKFZp586K0717; Factor interacting with PAP; FIP1 like 1; FIP1-like 1 protein; FIP1L1 cleavage and polyadenylation specific factor subunit; FLJ33619; hFip1; Pre-mRNA 3'-end-processing factor FIP1; Rearranged in hypereosinophilia

          View more View less

          Gene Aliases: FIP1; FIP1L1; hFip1; RHE

          View more View less

          UniProt ID: (Human) Q6UN15

          View more View less

          Entrez Gene ID: (Human) 81608

          View more View less

          Function(s)
          protein binding poly(A) RNA binding
          Process(es)
          mRNA splicing, via spliceosome termination of RNA polymerase II transcription mRNA export from nucleus mRNA 3'-end processing
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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          Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

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