Product References
Neuroprotective Effect and Mechanism of Thiazolidinedione on Dopaminergic Neurons In Vivo and In Vitro in Parkinson's Disease.
PPAR research
Wang Y,Zhao W,Li G,Chen J,Guan X,Chen X,Guan Z
Thu Oct 01 00:00:00 EDT 2020
Novel findings on ultrastructural protection of skeletal muscle fibers during hibernation of Daurian ground squirrels: Mitochondria, nuclei, cytoskeleton, glycogen.
Journal of cellular physiology
Wang Z,Jiang SF,Cao J,Liu K,Xu SH,Arfat Y,Guo QL,Chang H,Goswami N,Hinghofer-Szalkay H,Gao YF
Thu Aug 01 00:00:00 EDT 2019
Proteomic Analysis and Biochemical Correlates of Mitochondrial Dysfunction after Low-Intensity Primary Blast Exposure.
Journal of neurotrauma
Song H,Chen M,Chen C,Cui J,Johnson CE,Cheng J,Wang X,Swerdlow RH,DePalma RG,Xia W,Gu Z
Wed May 15 00:00:00 EDT 2019
Mitochondrial Dynamics Is Critical for the Full Pluripotency and Embryonic Developmental Potential of Pluripotent Stem Cells.
Cell metabolism
Zhong X,Cui P,Cai Y,Wang L,He X,Long P,Lu K,Yan R,Zhang Y,Pan X,Zhao X,Li W,Zhang H,Zhou Q,Gao P
Tue Apr 02 00:00:00 EDT 2019
Roles of mitochondrial fission inhibition in developmental fluoride neurotoxicity: mechanisms of action in vitro and associations with cognition in rats and children.
Archives of toxicology
Zhao Q,Niu Q,Chen J,Xia T,Zhou G,Li P,Dong L,Xu C,Tian Z,Luo C,Liu L,Zhang S,Wang A
Fri Mar 01 00:00:00 EST 2019
Roles of mitochondrial fission inhibition in developmental fluoride neurotoxicity: mechanisms of action in vitro and associations with cognition in rats and children.
Archives of toxicology
Zhao Q,Niu Q,Chen J,Xia T,Zhou G,Li P,Dong L,Xu C,Tian Z,Luo C,Liu L,Zhang S,Wang A
Fri Mar 01 00:00:00 EST 2019
Hepatic HKDC1 Expression Contributes to Liver Metabolism.
Endocrinology
Pusec CM,De Jesus A,Khan MW,Terry AR,Ludvik AE,Xu K,Giancola N,Pervaiz H,Daviau Smith E,Ding X,Harrison S,Chandel NS,Becker TC,Hay N,Ardehali H,Cordoba-Chacon J,Layden BT
Fri Feb 01 00:00:00 EST 2019
Mitochondrial division inhibitor 1 reduces dynamin-related protein 1 and mitochondrial fission activity.
Human molecular genetics
Manczak M,Kandimalla R,Yin X,Reddy PH
Tue Jan 15 00:00:00 EST 2019
Fibroblast growth factor 18 exerts anti-osteoarthritic effects through PI3K-AKT signaling and mitochondrial fusion and fission.
Pharmacological research
Yao X,Zhang J,Jing X,Ye Y,Guo J,Sun K,Guo F
Tue Jan 01 00:00:00 EST 2019
Mitochondrial dysfunction and mitophagy defect triggered by heterozygous GBA mutations.
Autophagy
Li H,Ham A,Ma TC,Kuo SH,Kanter E,Kim D,Ko HS,Quan Y,Sardi SP,Li A,Arancio O,Kang UJ,Sulzer D,Tang G
Tue Jan 01 00:00:00 EST 2019
Loss of the mitochondrial i-AAA protease YME1L leads to ocular dysfunction and spinal axonopathy.
EMBO molecular medicine
Sprenger HG,Wani G,Hesseling A,König T,Patron M,MacVicar T,Ahola S,Wai T,Barth E,Rugarli EI,Bergami M,Langer T
Tue Jan 01 00:00:00 EST 2019
A high-fat diet impairs mitochondrial biogenesis, mitochondrial dynamics, and the respiratory chain complex in rat myocardial tissues.
Journal of cellular biochemistry
Chen D,Li X,Zhang L,Zhu M,Gao L
Thu Nov 01 00:00:00 EDT 2018
Polybrene induces neural degeneration by bidirectional Ca2+ influx-dependent mitochondrial and ER-mitochondrial dynamics.
Cell death & disease
Bao F,Shi H,Gao M,Yang L,Zhou L,Zhao Q,Wu Y,Chen K,Xiang G,Long Q,Guo J,Zhang J,Liu X
Thu Sep 20 00:00:00 EDT 2018
Mutant APP and amyloid beta-induced defective autophagy, mitophagy, mitochondrial structural and functional changes and synaptic damage in hippocampal neurons from Alzheimer's disease.
Human molecular genetics
Reddy PH,Yin X,Manczak M,Kumar S,Pradeepkiran JA,Vijayan M,Reddy AP
Sun Jul 15 00:00:00 EDT 2018
AMPK/FIS1-Mediated Mitophagy Is Required for Self-Renewal of Human AML Stem Cells.
Cell stem cell
Pei S,Minhajuddin M,Adane B,Khan N,Stevens BM,Mack SC,Lai S,Rich JN,Inguva A,Shannon KM,Kim H,Tan AC,Myers JR,Ashton JM,Neff T,Pollyea DA,Smith CA,Jordan CT
Thu Jul 05 00:00:00 EDT 2018
AMPK/FIS1-Mediated Mitophagy Is Required for Self-Renewal of Human AML Stem Cells.
Cell stem cell
Pei S,Minhajuddin M,Adane B,Khan N,Stevens BM,Mack SC,Lai S,Rich JN,Inguva A,Shannon KM,Kim H,Tan AC,Myers JR,Ashton JM,Neff T,Pollyea DA,Smith CA,Jordan CT
Thu Jul 05 00:00:00 EDT 2018
Hippocampal mutant APP and amyloid beta-induced cognitive decline, dendritic spine loss, defective autophagy, mitophagy and mitochondrial abnormalities in a mouse model of Alzheimer's disease.
Human molecular genetics
Manczak M,Kandimalla R,Yin X,Reddy PH
Sun Apr 15 00:00:00 EDT 2018
GLUT10 maintains the integrity of major arteries through regulation of redox homeostasis and mitochondrial function.
Human molecular genetics
Syu YW,Lai HW,Jiang CL,Tsai HY,Lin CC,Lee YC
Mon Jan 15 00:00:00 EST 2018
INF2-mediated actin polymerization at the ER stimulates mitochondrial calcium uptake, inner membrane constriction, and division.
The Journal of cell biology
Chakrabarti R,Ji WK,Stan RV,de Juan Sanz J,Ryan TA,Higgs HN
Tue Jan 02 00:00:00 EST 2018
Hippocampal phosphorylated tau induced cognitive decline, dendritic spine loss and mitochondrial abnormalities in a mouse model of Alzheimer's disease.
Human molecular genetics
Kandimalla R,Manczak M,Yin X,Wang R,Reddy PH
Mon Jan 01 00:00:00 EST 2018
Receptor-mediated Drp1 oligomerization on endoplasmic reticulum.
The Journal of cell biology
Ji WK,Chakrabarti R,Fan X,Schoenfeld L,Strack S,Higgs HN
Mon Dec 04 00:00:00 EST 2017
Receptor-mediated Drp1 oligomerization on endoplasmic reticulum.
The Journal of cell biology
Ji WK,Chakrabarti R,Fan X,Schoenfeld L,Strack S,Higgs HN
Mon Dec 04 00:00:00 EST 2017
Hydrogen Sulphide modulating mitochondrial morphology to promote mitophagy in endothelial cells under high-glucose and high-palmitate.
Journal of cellular and molecular medicine
Liu N,Wu J,Zhang L,Gao Z,Sun Y,Yu M,Zhao Y,Dong S,Lu F,Zhang W
Fri Dec 01 00:00:00 EST 2017
p62-Mediated mitochondrial clustering attenuates apoptosis induced by mitochondrial depolarization.
Biochimica et biophysica acta. Molecular cell research
Xiao B,Deng X,Lim GGY,Zhou W,Saw WT,Zhou ZD,Lim KL,Tan EK
Sat Jul 01 00:00:00 EDT 2017
Phosphorylation of dynamin-related protein 1 at Ser616 regulates mitochondrial fission and is involved in mitochondrial calcium uniporter-mediated neutrophil polarization and chemotaxis.
Molecular immunology
Zheng X,Chen M,Meng X,Chu X,Cai C,Zou F
Sat Jul 01 00:00:00 EDT 2017
Fatty acid synthesis is critical for stem cell pluripotency via promoting mitochondrial fission.
The EMBO journal
Wang L,Zhang T,Wang L,Cai Y,Zhong X,He X,Hu L,Tian S,Wu M,Hui L,Zhang H,Gao P
Mon May 15 00:00:00 EDT 2017
Fatty acid synthesis is critical for stem cell pluripotency via promoting mitochondrial fission.
The EMBO journal
Wang L,Zhang T,Wang L,Cai Y,Zhong X,He X,Hu L,Tian S,Wu M,Hui L,Zhang H,Gao P
Mon May 15 00:00:00 EDT 2017
Ischemia-induced Drp1 and Fis1-mediated mitochondrial fission and right ventricular dysfunction in pulmonary hypertension.
Journal of molecular medicine (Berlin, Germany)
Tian L,Neuber-Hess M,Mewburn J,Dasgupta A,Dunham-Snary K,Wu D,Chen KH,Hong Z,Sharp WW,Kutty S,Archer SL
Sat Apr 01 00:00:00 EDT 2017
Salvianolic acid B inhibits mitochondrial dysfunction by up-regulating mortalin.
Scientific reports
Liu Y,Hu Y,E Q,Zuo J,Yang L,Liu W
Thu Mar 02 00:00:00 EST 2017
Mitochondrial dynamics changes with age in an APPsw/PS1dE9 mouse model of Alzheimer's disease.
Neuroreport
Xu LL,Shen Y,Wang X,Wei LF,Wang P,Yang H,Wang CF,Xie ZH,Bi JZ
Wed Mar 01 00:00:00 EST 2017
Low-level laser therapy for beta amyloid toxicity in rat hippocampus.
Neurobiology of aging
Lu Y,Wang R,Dong Y,Tucker D,Zhao N,Ahmed ME,Zhu L,Liu TC,Cohen RM,Zhang Q
Sun Jan 01 00:00:00 EST 2017
Sirtuin 5 protects mitochondria from fragmentation and degradation during starvation.
Biochimica et biophysica acta. Molecular cell research
Guedouari H,Daigle T,Scorrano L,Hebert-Chatelain E
Sun Jan 01 00:00:00 EST 2017
AP39, a Mitochondria-Targeted Hydrogen Sulfide Donor, Supports Cellular Bioenergetics and Protects against Alzheimer's Disease by Preserving Mitochondrial Function in APP/PS1 Mice and Neurons.
Oxidative medicine and cellular longevity
Zhao FL,Fang F,Qiao PF,Yan N,Gao D,Yan Y
Mon Dec 26 00:00:00 EST 2016
Resveratrol Induces Cancer Cell Apoptosis through MiR-326/PKM2-Mediated ER Stress and Mitochondrial Fission.
Journal of agricultural and food chemistry
Wu H,Wang Y,Wu C,Yang P,Li H,Li Z
Wed Dec 14 00:00:00 EST 2016
Protective effects of reduced dynamin-related protein 1 against amyloid beta-induced mitochondrial dysfunction and synaptic damage in Alzheimer's disease.
Human molecular genetics
Manczak M,Kandimalla R,Fry D,Sesaki H,Reddy PH
Thu Dec 01 00:00:00 EST 2016
Quantification and Characterization of UVB-Induced Mitochondrial Fragmentation in Normal Primary Human Keratinocytes.
Scientific reports
Jugé R,Breugnot J,Da Silva C,Bordes S,Closs B,Aouacheria A
Wed Oct 12 00:00:00 EDT 2016
Dysfunctional tubular endoplasmic reticulum constitutes a pathological feature of Alzheimer's disease.
Molecular psychiatry
Sharoar MG,Shi Q,Ge Y,He W,Hu X,Perry G,Zhu X,Yan R
Thu Sep 01 00:00:00 EDT 2016
Autophagy plays a role in skeletal muscle mitochondrial biogenesis in an endurance exercise-trained condition.
The journal of physiological sciences : JPS
Ju JS,Jeon SI,Park JY,Lee JY,Lee SC,Cho KJ,Jeong JM
Thu Sep 01 00:00:00 EDT 2016
FUNDC1 regulates mitochondrial dynamics at the ER-mitochondrial contact site under hypoxic conditions.
The EMBO journal
Wu W,Lin C,Wu K,Jiang L,Wang X,Li W,Zhuang H,Zhang X,Chen H,Li S,Yang Y,Lu Y,Wang J,Zhu R,Zhang L,Sui S,Tan N,Zhao B,Zhang J,Li L,Feng D
Fri Jul 01 00:00:00 EDT 2016
Mitochondria-targeted molecules MitoQ and SS31 reduce mutant huntingtin-induced mitochondrial toxicity and synaptic damage in Huntington's disease.
Human molecular genetics
Yin X,Manczak M,Reddy PH
Sun May 01 00:00:00 EDT 2016
Mitochondria-targeted molecules MitoQ and SS31 reduce mutant huntingtin-induced mitochondrial toxicity and synaptic damage in Huntington's disease.
Human molecular genetics
Yin X,Manczak M,Reddy PH
Sun May 01 00:00:00 EDT 2016
Appoptosin interacts with mitochondrial outer-membrane fusion proteins and regulates mitochondrial morphology.
Journal of cell science
Zhang C,Shi Z,Zhang L,Zhou Z,Zheng X,Liu G,Bu G,Fraser PE,Xu H,Zhang YW
Tue Mar 01 00:00:00 EST 2016
Loss of OMA1 delays neurodegeneration by preventing stress-induced OPA1 processing in mitochondria.
The Journal of cell biology
Korwitz A,Merkwirth C,Richter-Dennerlein R,Tröder SE,Sprenger HG,Quirós PM,López-Otín C,Rugarli EI,Langer T
Mon Jan 18 00:00:00 EST 2016
Mitochondrial division inhibitor 1 protects against mutant huntingtin-induced abnormal mitochondrial dynamics and neuronal damage in Huntington's disease.
Human molecular genetics
Manczak M,Reddy PH
Sun Dec 20 00:00:00 EST 2015
Mitochondrial division inhibitor 1 protects against mutant huntingtin-induced abnormal mitochondrial dynamics and neuronal damage in Huntington's disease.
Human molecular genetics
Manczak M,Reddy PH
Sun Dec 20 00:00:00 EST 2015
RNA viruses promote activation of the NLRP3 inflammasome through a RIP1-RIP3-DRP1 signaling pathway.
Nature immunology
Wang X,Jiang W,Yan Y,Gong T,Han J,Tian Z,Zhou R
Mon Dec 01 00:00:00 EST 2014
PARK2/Parkin-mediated mitochondrial clearance contributes to proteasome activation during slow-twitch muscle atrophy via NFE2L1 nuclear translocation.
Autophagy
Furuya N,Ikeda S,Sato S,Soma S,Ezaki J,Oliva Trejo JA,Takeda-Ezaki M,Fujimura T,Arikawa-Hirasawa E,Tada N,Komatsu M,Tanaka K,Kominami E,Hattori N,Ueno T
Tue Apr 01 00:00:00 EDT 2014
The i-AAA protease YME1L and OMA1 cleave OPA1 to balance mitochondrial fusion and fission.
The Journal of cell biology
Anand R,Wai T,Baker MJ,Kladt N,Schauss AC,Rugarli E,Langer T
Mon Mar 17 00:00:00 EDT 2014
Mutations in Fis1 disrupt orderly disposal of defective mitochondria.
Molecular biology of the cell
Shen Q,Yamano K,Head BP,Kawajiri S,Cheung JT,Wang C,Cho JH,Hattori N,Youle RJ,van der Bliek AM
Wed Jan 01 00:00:00 EST 2014
Mutations in Fis1 disrupt orderly disposal of defective mitochondria.
Molecular biology of the cell
Shen Q,Yamano K,Head BP,Kawajiri S,Cheung JT,Wang C,Cho JH,Hattori N,Youle RJ,van der Bliek AM
Wed Jan 01 00:00:00 EST 2014
Inhibition of mitochondrial fragmentation diminishes Huntington's disease-associated neurodegeneration.
The Journal of clinical investigation
Guo X,Disatnik MH,Monbureau M,Shamloo M,Mochly-Rosen D,Qi X
Sun Dec 01 00:00:00 EST 2013
Loss of Yme1L perturbates mitochondrial dynamics.
Cell death & disease
Ruan Y,Li H,Zhang K,Jian F,Tang J,Song Z
Thu Oct 31 00:00:00 EDT 2013
Mitochondrial abnormalities in temporal lobe of autistic brain.
Neurobiology of disease
Tang G,Gutierrez Rios P,Kuo SH,Akman HO,Rosoklija G,Tanji K,Dwork A,Schon EA,Dimauro S,Goldman J,Sulzer D
Sat Jun 01 00:00:00 EDT 2013
Mitochondrial abnormalities in temporal lobe of autistic brain.
Neurobiology of disease
Tang G,Gutierrez Rios P,Kuo SH,Akman HO,Rosoklija G,Tanji K,Dwork A,Schon EA,Dimauro S,Goldman J,Sulzer D
Sat Jun 01 00:00:00 EDT 2013
A novel Drp1 inhibitor diminishes aberrant mitochondrial fission and neurotoxicity.
Journal of cell science
Qi X,Qvit N,Su YC,Mochly-Rosen D
Fri Feb 01 00:00:00 EST 2013
A novel Drp1 inhibitor diminishes aberrant mitochondrial fission and neurotoxicity.
Journal of cell science
Qi X,Qvit N,Su YC,Mochly-Rosen D
Fri Feb 01 00:00:00 EST 2013
Dynamin-related protein 1 heterozygote knockout mice do not have synaptic and mitochondrial deficiencies.
Biochimica et biophysica acta
Manczak M,Sesaki H,Kageyama Y,Reddy PH
Fri Jun 01 00:00:00 EDT 2012
Dynamin-related protein 1 heterozygote knockout mice do not have synaptic and mitochondrial deficiencies.
Biochimica et biophysica acta
Manczak M,Sesaki H,Kageyama Y,Reddy PH
Fri Jun 01 00:00:00 EDT 2012
Impaired mitochondrial biogenesis, defective axonal transport of mitochondria, abnormal mitochondrial dynamics and synaptic degeneration in a mouse model of Alzheimer's disease.
Human molecular genetics
Calkins MJ,Manczak M,Mao P,Shirendeb U,Reddy PH
Thu Dec 01 00:00:00 EST 2011
Impaired mitochondrial dynamics and abnormal interaction of amyloid beta with mitochondrial protein Drp1 in neurons from patients with Alzheimer's disease: implications for neuronal damage.
Human molecular genetics
Manczak M,Calkins MJ,Reddy PH
Fri Jul 01 00:00:00 EDT 2011
Abnormal mitochondrial dynamics, mitochondrial loss and mutant huntingtin oligomers in Huntington's disease: implications for selective neuronal damage.
Human molecular genetics
Shirendeb U,Reddy AP,Manczak M,Calkins MJ,Mao P,Tagle DA,Reddy PH
Fri Apr 01 00:00:00 EDT 2011
Abnormal mitochondrial dynamics, mitochondrial loss and mutant huntingtin oligomers in Huntington's disease: implications for selective neuronal damage.
Human molecular genetics
Shirendeb U,Reddy AP,Manczak M,Calkins MJ,Mao P,Tagle DA,Reddy PH
Fri Apr 01 00:00:00 EDT 2011
Mitochondria-targeted antioxidants protect against amyloid-beta toxicity in Alzheimer's disease neurons.
Journal of Alzheimer's disease : JAD
Manczak M,Mao P,Calkins MJ,Cornea A,Reddy AP,Murphy MP,Szeto HH,Park B,Reddy PH
Mon Sep 13 00:00:00 EDT 2010