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Invitrogen
FKBP6 Polyclonal Antibody
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Product Details
PA5-77097
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant full length Human FKBP6.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Target Information
FKBP6 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. FKBP6 is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin.This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. This protein is involved in palate formation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 36 kDa FK506 binding protein; 36 kDa FK506-binding protein; 36 kDa FKBP; 36kD FKBP6; FK506 binding protein 6, 36kDa; FK506-binding protein 6; FK506-binding protein 6 (36kD); FKBP prolyl isomerase 6; FKBP-6; Immunophilin FKBP36; Inactive peptidyl-prolyl cis-trans isomerase FKBP6; Inactive PPIase FKBP6; MGC87179; peptidyl-prolyl cis-trans isomerase FKBP6; PPIase FKBP6; rotamase; unnamed protein product
Gene Aliases: 1700008G22Rik; 36kDa; As; AU017274; D5Ertd724e; FKBP-36; FKBP-6; FKBP36; FKBP6; PPiase; SPGF77
UniProt ID: (Human) O75344, (Mouse) Q91XW8, (Rat) D3ZQF4
Entrez Gene ID: (Human) 8468, (Mouse) 94244, (Rat) 288597
protein folding
spermatogenesis
cell differentiation
gene silencing by RNA
piRNA metabolic process
positive regulation of viral genome replication
meiotic cell cycle
transposable element silencing by piRNA-mediated DNA methylation
protein peptidyl-prolyl isomerization
meiotic nuclear division
peptidyl-proline modification
DNA methylation involved in gamete generation
chaperone-mediated protein folding
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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