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This gene encodes a member of the major facilitator superfamily of transporter proteins. The encoded protein is a heme transporter that may play a critical role in erythropoiesis by protecting developing erythroid cells from heme toxicity. This gene may play a role in posterior column ataxia with retinitis pigmentosa and the hematological disorder Diamond-Blackfan syndrome.
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Protein Aliases: eline leukemia virus subgroup C cellular receptor 1; feline leukemia virus subgroup C cellular receptor 1; Feline leukemia virus subgroup C receptor; Feline leukemia virus subgroup C receptor-related protein 1; FLVCR protein; Major facilitator superfamily domain containing 7B; Mfsd7b
Gene Aliases: 9630055N22Rik; AXPC1; FLVCR; FLVCR1; MFSD7B; PCA; PCARP
UniProt ID: (Human) Q9Y5Y0, (Mouse) B2RXV4
Entrez Gene ID: (Human) 28982, (Mouse) 226844
Molecular Function:
transporter
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