Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
FIGURE: 1 / 3
Recommended positive controls: A549, H1299, Mouse liver.
Predicted reactivity: Mouse (81%), Rat (83%), Dog (85%), Rabbit (84%), Rhesus Monkey (93%), Chimpanzee (100%), Bovine (82%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The mammalian flavin-containing monooxygenases (FMO; EC 1.14.13.8) represent a multigene family whose gene products are localized in the endoplasmic reticulum of many tissues. These enzymes catalyze the NADPH-dependent oxidative metabolism of many drugs, pesticides, and other foreign compounds. Their substrates are soft nucleophiles with an electron-rich center, typically a nitrogen, sulfur or phosphorus-containing functional group, as the site for oxidative attack by the enzyme.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Dimethylaniline monooxygenase [N-oxide-forming] 3; Dimethylaniline oxidase 3; Flavin-containing monooxygenase 3; FMO 3; FMO form 2; FMO II; Hepatic flavin-containing monooxygenase 3; hepatic flavin-containing monooxygenase-3; MGC34400; Trimethylamine monooxygenase
Gene Aliases: AW111792; dJ127D3.1; FMO3; FMOII; TMAU
UniProt ID: (Human) P31513, (Mouse) P97501
Entrez Gene ID: (Human) 2328, (Mouse) 14262
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