|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 122 and 394 of Human FMO3|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 10% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-27916 targets FMO3 in WB and IHC (P) applications and shows reactivity with Human and mouse samples.
The PA5-27916 immunogen is recombinant fragment corresponding to a region within amino acids 122 and 394 of Human FMO3.
The mammalian flavin-containing monooxygenases (FMO; EC 184.108.40.206) represent a multigene family whose gene products are localized in the endoplasmic reticulum of many tissues. These enzymes catalyze the NADPH-dependent oxidative metabolism of many drugs, pesticides, and other foreign compounds. Their substrates are soft nucleophiles with an electron-rich center, typically a nitrogen, sulfur or phosphorus-containing functional group, as the site for oxidative attack by the enzyme (Ziegler, 1990 [PubMed 2203193]; Hines et al., 1994 [PubMed 8128486]).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Dimethylaniline monooxygenase [N-oxide-forming] 3; Dimethylaniline oxidase 3; dJ127D3.1; FMO 3; FMO form 2; FMO II; FMOII; Hepatic flavin-containing monooxygenase 3; hepatic flavin-containing monooxygenase-3; TMAU; Trimethylamine monooxygenase
Gene Aliases: AW111792; dJ127D3.1; FMO3; FMOII; TMAU
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