FN3K catalyzes phosphorylation of fructosamines formed by glycation, the nonenzymatic reaction of glucose with primary amines followed by Amadori rearrangement. Phosphorylation of fructosamines may initiate metabolism of the modified amine and result in deglycation of glycated proteins.
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Protein Aliases: fructosamine 3-kinase; Fructosamine-3-kinase; Protein-psicosamine 3-kinase FN3K; Protein-ribulosamine 3-kinase FN3K
Gene Aliases: 2310074G21Rik; FN3K; Fnsk
Molecular Function: kinase