Invitrogen

FN3K Polyclonal Antibody

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FN3K Antibody in Western Blot (WB) — Western blot analysis of FN3K on rat thymus tissue lysate. The sample was probed with a FN3K polyclonal antibody (Product # PA5-70339) using a primary antibody dilution of 1.0 µg/mL.

Product Details

Tested Applications

Dilution

Western Blot (WB)

1.0 µg/mL

Product Specifications

Species Reactivity

Bovine, Dog, Horse, Guinea pig, Human, Mouse, Rabbit, Rat, Yeast

Host / Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

synthetic peptide directed towards the N-terminal region of rat FN3K

Conjugate

Unconjugated

Form

Liquid

Purification

Affinity chromatography

Storage buffer

PBS with 2% sucrose

Contains

0.09% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

RRID

AB_2690936

Product Specific Information

This target displays homology in the following species: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 79%

Target Information

FN3K catalyzes phosphorylation of fructosamines formed by glycation, the nonenzymatic reaction of glucose with primary amines followed by Amadori rearrangement. Phosphorylation of fructosamines may initiate metabolism of the modified amine and result in deglycation of glycated proteins (Delpierre et al., 2000 [PubMed 11016445]).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: fructosamine 3 kinase; fructosamine 3-kinase; Fructosamine-3-kinase; Protein-psicosamine 3-kinase FN3K; Protein-ribulosamine 3-kinase FN3K

Gene Aliases: 2310074G21Rik; BOS_19373; FN3K; Fnsk

UniProt ID: (Human) Q9H479, (Mouse) Q9ER35

Entrez Gene ID: (Bovine) 539709, (Dog) 608337, (Human) 64122, (Rat) 498034, (Guinea pig) 100718567, (Mouse) 63828, (Rabbit) 100346330

phosphorylation fructosamine metabolic process epithelial cell differentiation fructoselysine metabolic process post-translational protein modification

Process(es)

kinase activity fructosamine-3-kinase activity phosphofructokinase activity phosphorylase kinase regulator activity cobinamide kinase activity phytol kinase activity phosphatidylinositol phosphate kinase activity cyclin-dependent protein serine/threonine kinase regulator activity transferase activity transferase activity, transferring phosphorus-containing groups phenol kinase activity cyclin-dependent protein kinase activating kinase regulator activity inositol tetrakisphosphate 2-kinase activity heptose 7-phosphate kinase activity aminoglycoside phosphotransferase activity phosphatidylinositol 3-kinase activity eukaryotic elongation factor-2 kinase regulator activity eukaryotic elongation factor-2 kinase activator activity LPPG:FO 2-phospho-L-lactate transferase activity cytidine kinase activity glycerate 2-kinase activity (S)-lactate 2-kinase activity phosphoserine:homoserine phosphotransferase activity L-seryl-tRNA(Sec) kinase activity phosphocholine transferase activity polynucleotide 5'-hydroxyl-kinase activity ATP-dependent polynucleotide kinase activity GTP-dependent polynucleotide kinase activity farnesol kinase activity CTP:2-trans,-6-trans-farnesol kinase activity geraniol kinase activity geranylgeraniol kinase activity CTP:geranylgeraniol kinase activity prenol kinase activity 1-phosphatidylinositol-5-kinase activity 1-phosphatidylinositol-3-phosphate 4-kinase activity phosphatidylinositol-3,4-bisphosphate 5-kinase activity phosphatidylinositol bisphosphate kinase activity inositol-3,4,6-trisphosphate 1-kinase activity inositol 5-diphosphate pentakisphosphate 5-kinase activity inositol diphosphate tetrakisphosphate kinase activity