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Immunogen sequence: NGETAIGAEN SEKIDENSDK EMEVEESPEK IKVQTTPKVE EEQDLKFQIG ELANTLTSKF EFLGINRQSI SNFHVLLLQT ETRIAD
Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 92%.
FNBP4 encodes a protein containing two tryptophan-rich WW domains that binds the proline-rich formin homology 1 domains of formin family proteins, suggesting a role in the regulation of cytoskeletal dynamics during cell division and migration. It also binds intersectin family proteins suggesting a role in the maintenance of membrane curvature at sites of nascent vesicle formation. Naturally occurring mutations in this gene are associated with Waardenburg anophthalmia syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Formin-binding protein 30; Formin-binding protein 4
Gene Aliases: FBP30; FNBP4; KIAA1014
UniProt ID: (Human) Q8N3X1
Entrez Gene ID: (Human) 23360
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