Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
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Immunogen sequence: DRPPSPVNVT VTHLRANSAT VSWDVPEGNI VIGYSISQQR QNGPGQRVIR EVNTTTRACA LWGLAEDSDY TVQVRSIGLR GESPPGPRVH FRTLKGSDRL PSNSSSPGDI TVEGLDGERP LQT
Acts as an anti-inflammatory factor in the intestine and colon. Binds to and acts on macrophages to downregulate pro-inflammatory gene expression. Affects key macrophage functions, including phagocytosis, by downregulating many key pathways for macrophage activation, partly via by STAT3 activation and signaling. May be required to dampen the immunological response in colitis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Fibronectin type III domain-containing protein 4; fibronectin type III repeat containing protein 1; Fibronectin type III repeat-containing protein 1
Gene Aliases: 2810430J06Rik; 6330410H20Rik; AB030187; AI838506; AW487863; Fndc4; Fnmp1; FRCP1
UniProt ID: (Mouse) Q3TR08
Entrez Gene ID: (Mouse) 64339
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