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Bethyl Laboratories
FNIP1 Polyclonal Antibody
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Product Details
A305-767A
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A region between residue 775 to 825 of human Folliculin-interacting protein 1.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
phosphate/tris citrate, pH 7.0 to 8.0
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
FNIP1 encodes a protein that binds to the tumor suppressor protein folliculin and to AMP-activated protein kinase (AMPK). The encoded protein participates in the regulation of cellular metabolism and nutrient sensing by modulating the AMPK and target of rapamycin signaling pathways. This gene has a closely related paralog that encodes a protein with similar binding activities. Both related proteins also associate with the molecular chaperone heat shock protein-90 (Hsp90) and negatively regulate its ATPase activity and facilitate its association with folliculin. Diseases associated with FNIP1 include Birt-Hogg-Dube Syndrome and Pleural Disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Folliculin-interacting protein 1
Gene Aliases: FNIP1; KIAA1961
UniProt ID: (Human) Q8TF40
Entrez Gene ID: (Human) 96459
negative regulation of transcription from RNA polymerase II promoter
regulation of protein phosphorylation
positive regulation of protein phosphorylation
immature B cell differentiation
positive regulation of B cell apoptotic process
cellular response to starvation
positive regulation of protein complex assembly
TOR signaling
negative regulation of TOR signaling
positive regulation of peptidyl-serine phosphorylation
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
positive regulation of GTPase activity
regulation of pro-B cell differentiation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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