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Invitrogen
FOLR2 Polyclonal Antibody
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FIGURE: 1 / 2
FOLR2 Antibody (PA5-77980) in IHC (P)
Folate receptor beta antibody detects Folate receptor beta protein at membrane on mouse prostate by immunohistochemical analysis. Sample: Paraffin-embedded mouse prostate. Folate receptor beta antibody (Product # PA5-77980) dilution: 1:500. Antigen Retrieval: EDTA based buffer, pH 8.0, 15 min.
Product Details
PA5-77980
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Hamster,
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human Folate receptor beta. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.025% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive Control: Jurkat, Raji, NCI-H929
Predicted Reactivity: Rat (84%), Rhesus Monkey (97%), Bovine (86%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
FOLR2 is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68% and 79% sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FBP; folate binding protein 2; Folate receptor 2; folate receptor 2 (fetal); folate receptor alpha; Folate receptor beta; Folate receptor, fetal/placental; Folate-binding protein 2; folate-binding protein, fetal/placental; FR-beta; Placental folate-binding protein
Gene Aliases: BETA-HFR; FBP; FBP/PL-1; FBP2; Folbp-2; Folbp2; FOLR1; FOLR2; FR-BETA; FR-P3; FRbeta
UniProt ID: (Human) P14207, (Mouse) Q05685
Entrez Gene ID: (Human) 2350, (Mouse) 14276
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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