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Bethyl Laboratories
FOP Polyclonal Antibody
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FIGURE: 1 / 1
FOP Antibody (A301-860A) in WB
Detection of human FOP by western blot and immunoprecipitation. Samples: Whole cell lysate from HeLa (5, 15 and 50 µg for WB; 1 mg for IP, 20% of IP loaded) and HEK293T (T; 50 µg) cells. Antibodies: Affinity purified rabbit anti-FOP antibody (Product # A301-860A) used for WB at 0.4 µg/mL (A) and 1 µg/mL (B) and used for IP at 3 µg/mg lysate. FOP was also immunoprecipitated by rabbit anti-FOP antibody A301-861A, which recognizes a downstream epitope. Detection: Chemiluminescence with exposure times of 1 minute (A) and 10 seconds (B).
Product Details
A301-860A
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residue 225 and 275 of human FGFR1 oncogene partner.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
tris citrate/phosphate, pH 7-8
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
This gene encodes a largely hydrophilic protein postulated to be a leucine-rich protein family member. A t(6;8)(q27;p11) chromosomal translocation, fusing this gene and the fibroblast growth factor receptor 1 (FGFR1) gene, has been found in cases of myeloproliferative disorder. The resulting chimeric protein contains the N-terminal leucine-rich region of this encoded protein fused to the catalytic domain of FGFR1. This gene is thought to play an important role in normal proliferation and differentiation of the erythroid lineage. Alternatively spliced transcript variants that encode different proteins have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Centrosomal protein 43; FGFR1 oncogene partner; fibroblast growth factor receptor 1 oncogene partner; unnamed protein product
Gene Aliases: CEP43; FGFR1OP; FOP
UniProt ID: (Human) O95684
Entrez Gene ID: (Human) 11116
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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