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Abnova
FOSB Polyclonal Antibody, MaxPab™
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Product Details
H00002354-B01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
FOSB (AAH40197.1, 1 a.a. approximately 289 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MPGSFVPTVT AITTSQDLQW LVQPTLISSM AQSQGQPLAS QPPVVDPYDM PGTSYSTPGM SGYSSGGASG SGGPSTSGTT SGPGPARPAR ARPRRPREET LTPEEEEKRR VRRERNKLAA AKCRNRRREL TDRLQAETDQ LEEEKAELES EIAELQKEKE RLEFVLVAHK PGCKIPYEEG PGPGPLAEVR DLPGSAPAKE DGFSWLLPPP PPPPLPFQTS QDAPPNLTAS LFTHSEVQVL GDPFPVVNPS YTSSFVLTCP EVSAFAGAQR TSGSDQPSDP LNSPSLLAL
Target Information
c-FOS is a nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. It has a critical function in regulating the development of cells destined to form and maintain the skeleton, and is thought to have an important role in signal transduction, cell proliferation and differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: activator protein 1; DKFZp686C0818; FBJ murine osteosarcoma viral oncogene homolog B; fos b; FOSB; FosB proto-oncogene, AP-1 trancription factor subunit; FosB proto-oncogene, AP-1 transcription factor subunit; G0/G1 switch regulatory protein 3; GOS3 is human homolog of mouse FOSB gene; MGC42291; oncogene FOS-B; Protein FosB; Transcription factor AP-1 subunit FosB; unnamed protein product
Gene Aliases: AP-1; FOSB; G0S3; GOS3; GOSB
UniProt ID: (Human) P53539
Entrez Gene ID: (Human) 2354
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
double-stranded DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
sequence-specific DNA binding
sequence-specific double-stranded DNA binding
negative regulation of transcription from RNA polymerase II promoter
response to amphetamine
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
female pregnancy
response to xenobiotic stimulus
response to mechanical stimulus
response to progesterone
cellular response to hormone stimulus
response to nicotine
response to cocaine
response to morphine
response to ethanol
positive regulation of transcription from RNA polymerase II promoter
behavioral response to cocaine
response to corticosterone
response to cAMP
cellular response to calcium ion
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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