PA5-27158 targets FOXA2 in WB applications and shows reactivity with Human samples.
The PA5-27158 immunogen is a synthetic peptide corresponding to a region within amino acids 397 and 457 of FOXA2.
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This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific genes such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. This gene has been linked to sporadic cases of maturity-onset diabetes of the young. Transcript variants encoding different isoforms have been identified for this gene.
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Protein Aliases: beta; Forkhead box protein A2; hepatic nuclear factor-3-beta; hepatocyte nuclear factor 3; hepatocyte nuclear factor 3, beta; Hepatocyte nuclear factor 3-beta; HNF-3-beta; HNF-3B; HNF3B; TCF-3B; TCF3B; Transcription factor 3B
Gene Aliases: FOXA2; HNF3B; TCF3B
UniProt ID: (Human) Q9Y261
Entrez Gene ID: (Human) 3170