Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
This antibody is predicted to react with mouse and porcine based on sequence homology.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 32,000.
FOXC1 is a protein belonging to the forkhead family of transcription factors which is characterized by a distinct DNA-binding forkhead domain. The specific function of this protein is not known, however, it plays a role in the regulation of FGF19-FGFR4-MAPK pathway to promote both the development and maintenance of anterior segment structures within the eye. Mutations in this gene cause various glaucoma, iridogoniodysgenesis anomaly, Peters anomaly that includes central corneal leukoma, absence of the posterior corneal stroma and Descemetmembrane and Axenfeld-Rieger anomaly characterized by posterior corneal embryotoxon, iris adhesion to the Schwalbe line, hypertelorism, hypoplasia of the malar bones, congenital absence of some teeth and mental retardation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: forkhead box C1 protein; Forkhead box protein C1; forkhead, drosophila, homolog-like 7; forkhead-related activator 3; Forkhead-related protein FKHL7; Forkhead-related transcription factor 3; forkhead/winged helix-like transcription factor 7; FREAC-3; HGNC:3800; myeloid factor-delta
Gene Aliases: ARA; FKHL7; FOXC1; FREAC-3; FREAC3; IGDA; IHG1; IRID1; RIEG3
UniProt ID: (Human) Q12948
Entrez Gene ID: (Human) 2296
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn moreGet expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support