Proteintech

FOXC2 Polyclonal Antibody

FOXC2 Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 5

FOXC2 Antibody (23066-1-AP) in ICC/IF

Immunofluorescent analysis of ( 4% PFA ) fixed A375 cells using 23066-1-AP (FOXC2 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

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Product Details

23066-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

View 9 publications 9 publications

Immunohistochemistry (IHC)

View 2 publications 2 publications

Immunocytochemistry (ICC/IF)

1:50-1:500

View 2 publications 2 publications

Product Specifications

Published species

Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

FOXC2 Fusion Protein Ag19378 (204-501 aa encoded by BC113437)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.29 mg/mL

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

This antibody specifically recognizes the 56 kDa FOXC2 protein.^M
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Immunogen sequence: PKEAEKKVV IKSEAASPAL PVITKVETLS PESALQGSPR SAASTPAGSP DGSLPEHHAA APNGLPGFSV ENIMTLRTSP PGGELSPGAG RAGLVVPPLA LPYAAAPPAA YGQPCAQGLE AGAAGGYQCS MRAMSLYTGA ERPAHMCVPP ALDEALSDHP SGPTSPLSAL NLAAGQEGAL AATGHHHQHH GHHHPQAPPP PPAPQPQPTP QPGAAAAQAA SWYLNHSGDL NHLPGHTFAA QQQTFPNVRE MFNSHRLGIE NSTLGESQVS GNASCQLPYR STPPLYRHAA PYSYDCTKY (204-501 aa encoded by BC113437)

Target Information

Forkhead box protein C2 (FOXC2) is a transciptional activator and is characterized by a distinct DNA-binding forkhead domain. FOXC2 may be involved in the formation of special mesenchymal tissues. Mutations affecting the gene can cause lymphedema-distichiasis (LYD).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Differential Gene Expression Profiling in Alveolar Echinococcosis Identifies Potential Biomarkers Associated With Angiogenesis.

Open forum infectious diseases

Yimingjiang M,Aini A,Tuergan T,Zhang W

Wed Feb 01 00:00:00 UTC 2023

Exogenous interleukin 33 enhances the brain's lymphatic drainage and toxic protein clearance in acute traumatic brain injury mice.

Acta neuropathologica communications

Liu M,Huang J,Liu T,Yuan J,Lv C,Sha Z,Wu C,Jiang W,Liu X,Nie M,Chen Y,Dong S,Qian Y,Gao C,Fan Y,Wu D,Jiang R

Fri Apr 07 00:00:00 UTC 2023

Improving the Function of Meningeal Lymphatic Vessels to Promote Brain Edema Absorption after Traumatic Brain Injury.

Journal of neurotrauma

Liao J,Zhang M,Shi Z,Lu H,Wang L,Fan W,Tong X,Yan H

Wed Feb 01 00:00:00 UTC 2023

Stanniocalcin 1 promotes metastasis, lipid metabolism and cisplatin chemoresistance via the FOXC2/ITGB6 signaling axis in ovarian cancer.

Journal of experimental & clinical cancer research : CR

Lin F,Li X,Wang X,Sun H,Wang Z,Wang X

Thu Apr 07 00:00:00 UTC 2022

Stanniocalcin 1 promotes metastasis, lipid metabolism and cisplatin chemoresistance via the FOXC2/ITGB6 signaling axis in ovarian cancer.

Journal of experimental & clinical cancer research : CR

Lin F,Li X,Wang X,Sun H,Wang Z,Wang X

Thu Apr 07 00:00:00 UTC 2022

VEGF-C/VEGFR-3 axis protects against pressure-overload induced cardiac dysfunction through regulation of lymphangiogenesis.

Clinical and translational medicine

Lin QY,Zhang YL,Bai J,Liu JQ,Li HH

Mon Mar 01 00:00:00 UTC 2021

Long non-coding RNA GClnc1 knockdown suppresses progression of epithelial ovarian cancer by recruiting FOXC2 to disrupt the NOTCH1/NF-κB/Snail pathway.

Experimental cell research

Wu D,Ke Y,Xiao R,Liu J,Li Q,Wang Y

Mon Feb 01 00:00:00 UTC 2021

Long non-coding RNA GClnc1 knockdown suppresses progression of epithelial ovarian cancer by recruiting FOXC2 to disrupt the NOTCH1/NF-κB/Snail pathway.

Experimental cell research

Wu D,Ke Y,Xiao R,Liu J,Li Q,Wang Y

Mon Feb 01 00:00:00 UTC 2021

Decreased ZNF750 promotes angiogenesis in a paracrine manner via activating DANCR/miR-4707-3p/FOXC2 axis in esophageal squamous cell carcinoma.

Cell death & disease

Bi Y,Guo S,Xu X,Kong P,Cui H,Yan T,Ma Y,Cheng Y,Chen Y,Liu X,Zhang L,Cheng C,Xu E,Qian Y,Yang J,Song B,Li H,Wang F,Hu X,Liu X,Niu X,Zhai Y,Liu J,Li Y,Cheng X,Cui Y

Mon Apr 27 00:00:00 UTC 2020

Decreased ZNF750 promotes angiogenesis in a paracrine manner via activating DANCR/miR-4707-3p/FOXC2 axis in esophageal squamous cell carcinoma.

Cell death & disease

Bi Y,Guo S,Xu X,Kong P,Cui H,Yan T,Ma Y,Cheng Y,Chen Y,Liu X,Zhang L,Cheng C,Xu E,Qian Y,Yang J,Song B,Li H,Wang F,Hu X,Liu X,Niu X,Zhai Y,Liu J,Li Y,Cheng X,Cui Y

Mon Apr 27 00:00:00 UTC 2020

Hypoxia-induced feedback of HIF-1α and lncRNA-CF129 contributes to pancreatic cancer progression through stabilization of p53 protein.

Theranostics

Liu M,Zhong J,Zeng Z,Huang K,Ye Z,Deng S,Chen H,Xu F,Li Q,Zhao G

Tue Aug 25 00:00:00 UTC 2020

Naringin promotes osteogenic differentiation of bone marrow stromal cells by up-regulating Foxc2 expression via the IHH signaling pathway.

American journal of translational research

Lin FX,Du SX,Liu DZ,Hu QX,Yu GY,Wu CC,Zheng GZ,Xie D,Li XD,Chang B

Wed Sep 30 00:00:00 UTC 2020