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FOXE1 Polyclonal Antibody
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FIGURE: 1 / 2
FOXE1 Antibody (BS-0446R) in WB
Lane 1: mouse brain lysates Lane 2: mouse thyroid lysates probed with Anti TTF-2/FOXE1 Polyclonal Antibody, Unconjugated (bs-0446R) at 1:200 in 4°C. Followed by conjugation to secondary antibody (bs-0295G-HRP) at 1:3000 90 min in 37°C. Predicted band 41 kD. Observed band size: 41 kD.
Product Details
BS-0446R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human FOXE1, amino acids 101-200.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
This intronless gene belongs to the forkhead family of transcription factors, which is characterized by a distinct forkhead domain. This gene functions as a thyroid transcription factor which likely plays a crucial role in thyroid morphogenesis. Mutations in this gene are associated with congenital hypothyroidism and cleft palate with thyroid dysgenesis. The map localization of this gene suggests it may also be a candidate gene for squamous cell epithelioma and hereditary sensory neuropathy type I.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: forkhead box E1 (thyroid transcription factor 2); Forkhead box protein E1; Forkhead box protein E2; forkhead, drosophila, homolog-like 15; Forkhead-related protein FKHL15; HFKH4; HFKL5; HNF-3/fork head-like protein 5; Thyroid transcription factor 2; TTF-2
Gene Aliases: BAMLAZ; FKHL15; FOXE1; FOXE2; HFKH4; HFKL5; NMTC4; TITF2; TTF-2; TTF2
UniProt ID: (Human) O00358, (Mouse) Q8R2I0
Entrez Gene ID: (Human) 2304, (Rat) 192274, (Mouse) 110805
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
sequence-specific DNA binding
sequence-specific double-stranded DNA binding
winged helix/forkhead transcription factor
negative regulation of transcription from RNA polymerase II promoter
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
thyroid hormone generation
anatomical structure morphogenesis
cell migration
cell differentiation
thyroid gland development
hair follicle morphogenesis
positive regulation of transcription, DNA-templated
animal organ development
thymus development
embryonic organ morphogenesis
system development
palate development
hard palate development
soft palate development
chordate pharynx development
cranial skeletal system development
transcription from RNA polymerase II promoter
pharynx development
transcription, DNA-templated
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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