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Invitrogen
FOXM1 Polyclonal Antibody
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FIGURE: 1 / 1
FOXM1 Antibody (PA5149602) in ChIP
ChIP Assay of FOXM1 in K562 cells. ChIP-Exo-Seq composite graph for FOXM1 polyclonal antibody (Product # PA5149602). Strand-specific reads (blue: forward, red: reverse) and IgG controls (black: forward, grey: reverse) are plotted against the distance from a composite set of reference binding sites. The antibody exhibits robust target enrichment compared to a non-specific IgG control and precisely reveals its structural organization around the binding site.
Product Details
PA5149602
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human FOXM1
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Amount
50 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: GIAPLSSAGP GKEEKLLFGE GFSPLLPVQT IKEEEIQPGE EMPHLARPIK VESPPLEEWP SPAPSFKEES SHSWEDSSQS PTPRPKKSYS GL
Highest antigen sequence identity to the following orthologs: Mouse - 73%, Rat - 75%.
Target Information
FOXM1 (forkhead box protein M1) is a transcriptional factor regulating the expression of cell cycle genes essential for DNA replication and mitosis. FOXM1 plays a role in the control of cell proliferation and DNA break repairs participating in the DNA damage checkpoint response.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: cell proliferation-inducing gene 29 protein; FKH L16; FKHL 16; forkhead box M1-D; Forkhead box protein M1; Forkhead like 16; Forkhead, drosophila, homolog-like 16; Forkhead-related protein FKHL16; FOXM 1; FOXM 1c; Hepatocyte nuclear factor 3 forkhead homolog 11; hepatocyte nuclear factor-3/fork head homolog 11A; winged helix transcription factor; HFH 11; HFH-11; HNF 3; HNF-3/fork-head homolog 11; HNF3; INS 1; INS1; M-phase phosphoprotein 2; MPHOSPH 2; MPM 2; MPM-2 reactive phosphoprotein 2; MPP 2; PIG 29; TGT3; Transcription factor Trident; unnamed protein product; winged helix transcription factor; hepatocyte nuclear factor-3/fork head homolog 11B; Winged-helix factor from INS-1 cells
Gene Aliases: FKHL16; FOXM1; FOXM1A; FOXM1B; FOXM1C; HFH-11; HFH11; HNF-3; INS-1; MPHOSPH2; MPP-2; MPP2; PIG29; TRIDENT; WIN
UniProt ID: (Human) Q08050
Entrez Gene ID: (Human) 2305
G2/M transition of mitotic cell cycle
negative regulation of transcription from RNA polymerase II promoter
DNA repair
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
cellular response to DNA damage stimulus
regulation of mitotic cell cycle
positive regulation of cell proliferation
DNA damage response, signal transduction by p53 class mediator
negative regulation of stress-activated MAPK cascade
regulation of cell proliferation
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
regulation of Ras protein signal transduction
regulation of cell cycle
regulation of reactive oxygen species metabolic process
positive regulation of double-strand break repair
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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