The calculated molecular weight of FOXO3 is 71 kDa, but some experiments using a FOXO3a specific antibody showed the expression of a 90 kDa full-length FOXO3a protein (Full) and a 40 kDa processed FOXO3a product (Short).
USP48 is a protein containing domains that associate it with the peptidase family C19, also known as family 2 of ubiquitin carboxyl-terminal hydrolases. Family members function as deubiquitinating enzymes, recognizing and hydrolyzing the peptide bond at the C-terminal glycine of ubiquitin. Enzymes in peptidase family C19 are involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins.
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Protein Aliases: AF6q21 antibody; AF6q21 protein; AFX; AFX1; DAF16 antibody; DKFZp781A0677; FkhR; FKHR-LIKE 1; FKHR2 antibody; FKHRL1 antibody; FKHRL1P2 antibody; Forkhead Box O1; forkhead box O3A; Forkhead Box O4; Forkhead box protein O3; forkhead homolog (rhabdomyosarcoma) like 1; Forkhead in rhabdomyosarcoma-like 1; forkhead protein FKHR2; forkhead, Drosophila, homolog of, in rhabdomyosarcoma-like 1; FOXO1; FOXO4; in rhab; MGC120490; MGC12739; MGC31925; MLLT7
Gene Aliases: 1110048B16Rik; 2010203A17Rik; AF6q21; C76856; Fkhr2; FKHRL1; FKHRL1P2; FOXO2; FOXO3; FOXO3A